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Descriptor English: Thyroid Hormone Receptors beta
Descriptor Spanish: Receptores beta de Hormona Tiroidea
Descriptor receptores beta de hormonas tiroideas
Scope note: Receptores que poseen alta afinidad para las HORMONAS TIROIDEAS, especialmente por la TRIIODOTIRONINA. Esta clase de receptores se encuentran generalmente en el núcleo, donde regulan la trancripción del ADN. Están codificados por el gen THRB (también denominado NR1A2, THRB1 o ERBA2) y existen varias isoformas producidas por el empalme alternativo. Las mutaciones en el gen THRB son causa del SÍNDROME DE RESISTENCIA A LA HORMONA TIROIDEA.
Descriptor Portuguese: Receptores beta dos Hormônios Tireóideos
Descriptor French: Récepteurs bêta des hormones thyroïdiennes
Entry term(s): ERBA2 Gene Products
Gene Products, ERBA2
Gene Products, NR1A2
Gene Products, THRB
NR1A2 Gene Products
Receptors beta, Thyroid Hormone
THRB Gene Products
TR beta
Thyroid Hormone Receptor beta
Thyroid Hormone Receptor beta 1
Thyroid Hormone Receptor beta 2
Thyroid Hormone Receptor beta-1
Thyroid Hormone Receptor beta-2
c erbA beta
c-erbA beta
Tree number(s): D12.776.624.664.700.830.750
D12.776.826.850.750
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D037042
Scope note: High affinity receptors for THYROID HORMONES, especially TRIIODOTHYRONINE. These receptors are usually found in the nucleus where they regulate DNA transcription. They are encoded by the THRB gene (also known as NR1A2, THRB1, or ERBA2 gene) as several isoforms produced by alternative splicing. Mutations in the THRB gene cause THYROID HORMONE RESISTANCE SYNDROME.
Allowable Qualifiers: AD administration & dosage
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CH chemistry
CL classification
DE drug effects
DF deficiency
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PH physiology
RE radiation effects
TU therapeutic use
UL ultrastructure
Public MeSH Note: 2003; use RECEPTORS, THYROID HORMONE 1994-2002; THYROID HORMONE RECEPTOR BETA was indexed under RECEPTORS, THYROID HORMONE 2002-2005
History Note: 2003; use RECEPTORS, THYROID HORMONE 1994-2002
Entry Version: THYROID HORMONE RECEPT BETA
DeCS ID: 37517
Unique ID: D037042
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2003/01/01
Date of Entry: 2002/07/03
Revision Date: 2015/06/23
Thyroid Hormone Receptors beta - Preferred
Concept UI M0018634
Scope note High affinity receptors for THYROID HORMONES, especially TRIIODOTHYRONINE. These receptors are usually found in the nucleus where they regulate DNA transcription. They are encoded by the THRB gene (also known as NR1A2, THRB1, or ERBA2 gene) as several isoforms produced by alternative splicing. Mutations in the THRB gene cause THYROID HORMONE RESISTANCE SYNDROME.
Preferred term Thyroid Hormone Receptors beta
Entry term(s) ERBA2 Gene Products
Gene Products, ERBA2
Gene Products, NR1A2
Gene Products, THRB
NR1A2 Gene Products
Receptors beta, Thyroid Hormone
THRB Gene Products
TR beta
Thyroid Hormone Receptor beta
c erbA beta
c-erbA beta
Thyroid Hormone Receptor beta-2 - Narrower
Concept UI M0411732
Scope note An isoform produced by alternative splicing.
Preferred term Thyroid Hormone Receptor beta-2
Entry term(s) Thyroid Hormone Receptor beta 2
Thyroid Hormone Receptor beta-1 - Narrower
Concept UI M0411731
Scope note An isoform produced by alternative splicing.
Preferred term Thyroid Hormone Receptor beta-1
Entry term(s) Thyroid Hormone Receptor beta 1



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