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Descriptor English: Eukaryotic Initiation Factor-3
Descriptor Spanish: Factor 3 de Iniciación Eucariótica
Descriptor factor de iniciación eucariótico 3
Entry term(s) EIF-3
factor EIF-3 de iniciación de péptidos
Scope note: Factor de iniciación eucariótico con múltiples subunidades que contiene al menos 8 polipéptidos diferentes. Interviene en el reciclado de las unidades ribosómicas en el sitio de iniciación de la transcripción, promoviendo la disociación de subunidades ribosómicas no traslacionales. Está involucrado además en la promoción de la unión de un complejo ternario del FACTOR-2 DE INICIACIÓN EUCARIÓTICA; GTP; y ARNt INICIADOR en la subunidad ribosómica 40S.
Descriptor Portuguese: Fator de Iniciação 3 em Eucariotos
Descriptor French: Facteur-3 d'initiation eucaryote
Entry term(s): EIF-3
EIF3
EIF3 Protein, p42
EIF3 alpha
EIF3 epsilon
EIF3 gamma
EIF3 p110
EIF3 p42 Protein
EIF3-alpha
EIF3-beta
EIF3-epsilon
EIF3-gamma
EIF3-p48
EIF3-zeta
EIF3S3 Gene Product
EIF3S3 Protein
EIF3S4 Protein
Eukaryotic Initiation Factor 3
Eukaryotic Initiation Factor 3 p110
Eukaryotic Initiation Factor 3, Subunit 1
Eukaryotic Initiation Factor 3, Subunit 2
Eukaryotic Initiation Factor 3, Subunit 3
Eukaryotic Initiation Factor 3, Subunit 4
Eukaryotic Initiation Factor 3, Subunit 5
Eukaryotic Initiation Factor 3, Subunit 6
Eukaryotic Initiation Factor 3, Subunit 7
Eukaryotic Initiation Factor 3, Subunit 8
Eukaryotic Initiation Factor 3, beta Subunit
Eukaryotic Initiation Factor 3, delta Subunit
Eukaryotic Initiation Factor 3, gamma Subunit
Eukaryotic Initiation Factor 3, zeta Subunit
Eukaryotic Initiation Factor-3 p110
Eukaryotic Initiation Factor-3, Subunit 1
Eukaryotic Initiation Factor-3, Subunit 2
Eukaryotic Initiation Factor-3, Subunit 3
Eukaryotic Initiation Factor-3, Subunit 4
Eukaryotic Initiation Factor-3, Subunit 5
Eukaryotic Initiation Factor-3, Subunit 6
Eukaryotic Initiation Factor-3, Subunit 7
Eukaryotic Initiation Factor-3, Subunit 8
Eukaryotic Initiation Factor-3, beta Subunit
Eukaryotic Initiation Factor-3, delta Subunit
Eukaryotic Initiation Factor-3, gamma Subunit
Eukaryotic Initiation Factor-3, zeta Subunit
Eukaryotic Peptide Initiation Factor 3
Eukaryotic Peptide Initiation Factor 3, Subunit 1
Eukaryotic Peptide Initiation Factor 3, Subunit 2
Eukaryotic Peptide Initiation Factor 3, Subunit 3
Eukaryotic Peptide Initiation Factor 3, Subunit 4
Eukaryotic Peptide Initiation Factor 3, Subunit 5
Eukaryotic Peptide Initiation Factor 3, alpha Subunit
Eukaryotic Peptide Initiation Factor-3
Eukaryotic Peptide Initiation Factor-3, Subunit 1
Eukaryotic Peptide Initiation Factor-3, Subunit 2
Eukaryotic Peptide Initiation Factor-3, Subunit 3
Eukaryotic Peptide Initiation Factor-3, Subunit 4
Eukaryotic Peptide Initiation Factor-3, alpha Subunit
Eukaryotic Translation Initiation Factor 3, Subunit 8
Eukaryotic Translation Initiation Factor-3, Subunit 8
Gene Product, Int-6
INT6 Protein
Initiation Factor-3, Eukaryotic
Int 6 Gene Product
Int 6 Protein
Int-6 Gene Product
Int-6 Protein
Peptide Initiation Factor EIF 3
Peptide Initiation Factor EIF-3
p42 EIF3 Protein
Tree number(s): D12.776.835.725.868.437
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D039621
Scope note: A multisubunit eukaryotic initiation factor that contains at least 8 distinct polypeptides. It plays a role in recycling of ribosomal subunits to the site of transcription initiation by promoting the dissociation of non-translating ribosomal subunits. It also is involved in promoting the binding of a ternary complex of EUKARYOTIC INITIATION FACTOR-2; GTP; and INITIATOR TRNA to the 40S ribosomal subunit.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Peptide Initiation Factors (1990-2002)
Public MeSH Note: 2003; EIF-3 (now EUKARYOTIC INITIATION FACTOR-3) was indexed under PEPTIDE INITIATION FACTORS 1990-2002; EUKARYOTIC INITIATION FACTOR 3 P110 (now EUKARYOTIC INITIATION FACTOR-3) was indexed under PEPTIDE INITIATION FACTORS 2000-2002; EUKARYOTIC INITIATION FACTOR 3, SUBUNIT 4 (now EUKARYOTIC INITIATION FACTOR-3) was indexed under PEPTIDE INITIATION FACTORS 1999-2002; INT-6 PROTEIN (now EUKARYOTIC INITIATION FACTOR-3) was indexed under PEPTIDE INITIATION FACTORS 1995-2002
History Note: 2003; use EUKARYOTIC INITIATION FACTOR-3 (NM) 1990-2002
DeCS ID: 37526
Unique ID: D039621
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2003/01/01
Date of Entry: 2002/07/03
Revision Date: 2013/07/09
Eukaryotic Initiation Factor-3 - Preferred
Concept UI M0177967
Scope note A multisubunit eukaryotic initiation factor that contains at least 8 distinct polypeptides. It plays a role in recycling of ribosomal subunits to the site of transcription initiation by promoting the dissociation of non-translating ribosomal subunits. It also is involved in promoting the binding of a ternary complex of EUKARYOTIC INITIATION FACTOR-2; GTP; and INITIATOR TRNA to the 40S ribosomal subunit.
Preferred term Eukaryotic Initiation Factor-3
Entry term(s) EIF-3
EIF3
Eukaryotic Initiation Factor 3
Eukaryotic Peptide Initiation Factor 3
Eukaryotic Peptide Initiation Factor-3
Initiation Factor-3, Eukaryotic
Peptide Initiation Factor EIF 3
Peptide Initiation Factor EIF-3
Eukaryotic Initiation Factor-3, Subunit 2 - Narrower
Concept UI M0420012
Preferred term Eukaryotic Initiation Factor-3, Subunit 2
Entry term(s) EIF3-beta
Eukaryotic Initiation Factor 3, Subunit 2
Eukaryotic Initiation Factor 3, beta Subunit
Eukaryotic Initiation Factor-3, beta Subunit
Eukaryotic Peptide Initiation Factor 3, Subunit 2
Eukaryotic Peptide Initiation Factor-3, Subunit 2
Eukaryotic Initiation Factor-3, Subunit 3 - Narrower
Concept UI M0407774
Preferred term Eukaryotic Initiation Factor-3, Subunit 3
Entry term(s) EIF3 gamma
EIF3-gamma
EIF3S3 Gene Product
EIF3S3 Protein
Eukaryotic Initiation Factor 3, Subunit 3
Eukaryotic Initiation Factor 3, gamma Subunit
Eukaryotic Initiation Factor-3, gamma Subunit
Eukaryotic Peptide Initiation Factor 3, Subunit 3
Eukaryotic Peptide Initiation Factor-3, Subunit 3
Eukaryotic Initiation Factor-3, Subunit 8 - Narrower
Concept UI M0373801
Preferred term Eukaryotic Initiation Factor-3, Subunit 8
Entry term(s) EIF3 p110
Eukaryotic Initiation Factor 3 p110
Eukaryotic Initiation Factor 3, Subunit 8
Eukaryotic Initiation Factor-3 p110
Eukaryotic Translation Initiation Factor 3, Subunit 8
Eukaryotic Translation Initiation Factor-3, Subunit 8
Eukaryotic Initiation Factor-3, Subunit 5 - Narrower
Concept UI M0420013
Preferred term Eukaryotic Initiation Factor-3, Subunit 5
Entry term(s) EIF3 epsilon
EIF3-epsilon
Eukaryotic Initiation Factor 3, Subunit 5
Eukaryotic Initiation Factor 3, delta Subunit
Eukaryotic Initiation Factor-3, delta Subunit
Eukaryotic Peptide Initiation Factor 3, Subunit 5
Eukaryotic Initiation Factor-3, Subunit 6 - Narrower
Concept UI M0242820
Preferred term Eukaryotic Initiation Factor-3, Subunit 6
Entry term(s) EIF3-p48
Eukaryotic Initiation Factor 3, Subunit 6
Gene Product, Int-6
INT6 Protein
Int 6 Gene Product
Int 6 Protein
Int-6 Gene Product
Int-6 Protein
Eukaryotic Initiation Factor-3, Subunit 7 - Narrower
Concept UI M0420029
Preferred term Eukaryotic Initiation Factor-3, Subunit 7
Entry term(s) EIF3-zeta
Eukaryotic Initiation Factor 3, Subunit 7
Eukaryotic Initiation Factor 3, zeta Subunit
Eukaryotic Initiation Factor-3, zeta Subunit
Eukaryotic Initiation Factor-3, Subunit 1 - Narrower
Concept UI M0420011
Preferred term Eukaryotic Initiation Factor-3, Subunit 1
Entry term(s) EIF3 alpha
EIF3-alpha
Eukaryotic Initiation Factor 3, Subunit 1
Eukaryotic Peptide Initiation Factor 3, Subunit 1
Eukaryotic Peptide Initiation Factor 3, alpha Subunit
Eukaryotic Peptide Initiation Factor-3, Subunit 1
Eukaryotic Peptide Initiation Factor-3, alpha Subunit
Eukaryotic Initiation Factor-3, Subunit 4 - Narrower
Concept UI M0303455
Preferred term Eukaryotic Initiation Factor-3, Subunit 4
Entry term(s) EIF3 Protein, p42
EIF3 p42 Protein
EIF3S4 Protein
Eukaryotic Initiation Factor 3, Subunit 4
Eukaryotic Peptide Initiation Factor 3, Subunit 4
Eukaryotic Peptide Initiation Factor-3, Subunit 4
p42 EIF3 Protein



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