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Descriptor English: Prokaryotic Initiation Factor-2
Descriptor Spanish: Factor 2 Procariótico de Iniciación
Descriptor factor de iniciación procariótico 2
Entry term(s) factor IF-2 de iniciación de péptidos
Scope note: Es el mayor de los tres factores procarióticos de iniciación, con un tamaño molecular de aproximadamente 80 kDa. Actúa en el proceso de iniciación de la transcripción promoviendo la unión de ARNt-formilmetionina al sitio P del ribosoma 30S e impidiendo la unión incorrecta del ARNt de elongación al sitio de iniciación de la traducción.
Descriptor Portuguese: Fator de Iniciação 2 em Procariotos
Descriptor French: Facteur d'initiation procaryote 2
Entry term(s): IF2 Protein
Initiation Factor 2
Initiation Factor-2
Initiation Factor-2, Prokaryotic
Peptide Initiation Factor 2
Peptide Initiation Factor IF 2
Peptide Initiation Factor IF-2
Prokaryotic Initiation Factor 2
Translational Initiation Factor 2
infB Gene Product
infB Protein
Tree number(s): D12.776.835.725.934.562
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D039881
Scope note: The largest of the three prokaryotic initiation factors with a molecular size of approximately 80 kD. It functions in the transcription initiation process by promoting the binding of formylmethionine-tRNA to the P-site of the 30S ribosome and by preventing the incorrect binding of elongator tRNA to the translation initiation site.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Peptide Initiation Factors (1990-2002)
Public MeSH Note: 2003; PROKARYOTIC INITIATION FACTOR-2 was indexed under PEPTIDE INTIATION FACTORS 1990-2002; TRANSLATIONAL INITIATION FACTOR 2 was indexed under PEPTIDE INITIATION FACTORS 1997-2002
History Note: 2003; use PROKARYOTIC INITIATION FACTOR-2 (NM) 1990-2002
DeCS ID: 37530
Unique ID: D039881
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2003/01/01
Date of Entry: 2002/07/03
Prokaryotic Initiation Factor-2 - Preferred
Concept UI M0176255
Scope note The largest of the three prokaryotic initiation factors with a molecular size of approximately 80 kD. It functions in the transcription initiation process by promoting the binding of formylmethionine-tRNA to the P-site of the 30S ribosome and by preventing the incorrect binding of elongator tRNA to the translation initiation site.
Preferred term Prokaryotic Initiation Factor-2
Entry term(s) IF2 Protein
Initiation Factor 2
Initiation Factor-2
Initiation Factor-2, Prokaryotic
Peptide Initiation Factor 2
Peptide Initiation Factor IF 2
Peptide Initiation Factor IF-2
Prokaryotic Initiation Factor 2
Translational Initiation Factor 2
infB Gene Product
infB Protein



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