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Descriptor English: Prokaryotic Initiation Factor-1
Descriptor Spanish: Factor 1 Procariótico de Iniciación
Descriptor factor de iniciación procariótico 1
Entry term(s) factor IF-1 de iniciación de péptidos
Scope note: Es el menor de los tres factores procarióticos de iniciación, con un tamaño molecular de aproximadamente 8 kD. Se une cerca del sitio A de la subunidad 30S de los RIBOSOMAS y puede intervenir en la prevención de la unión temprana al ribosoma del FACTOR TU DE ELONGACIÓN PEPTÍDICA unido a aminoacilo-ARNt, durante la iniciación de una cadena peptídica (INICIACIÓN DE LA TRADUCCIÓN DE CADENAS PEPTÍDICAS).
Descriptor Portuguese: Fator de Iniciação 1 em Procariotos
Descriptor French: Facteur d'initiation procaryote 1
Entry term(s): IF-1, Initiation Factor
Initiation Factor IF 1
Initiation Factor IF-1
Initiation Factor-1, Prokaryotic
Peptide Initiation Factor 1, Prokaryotic
Peptide Initiation Factor IF 1
Peptide Initiation Factor IF-1
Peptide Initiation Factor-1, Prokaryotic
Prokaryotic Initiation Factor 1
Prokaryotic Peptide Initiation Factor 1
Prokaryotic Peptide Initiation Factor-1
Tree number(s): D12.776.835.725.934.374
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D039861
Scope note: The smallest of the three prokaryotic initiation factors with a molecular size of approximately 8 kD. It binds near the A-site of the 30S subunit of RIBOSOMES and may play a role in preventing premature addition of aminoacyl-tRNA-linked PEPTIDE ELONGATION FACTOR TU to the ribosome during the initiation of a peptide chain (PEPTIDE CHAIN INITIATION, TRANSLATIONAL).
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Eukaryotic Initiation Factor-1 (1989-2002)
Peptide Initiation Factors (1978-2002)
Public MeSH Note: 2003; for IF-1see EIF-1 1990-2002
History Note: 2003; for IF-1 use EUKARYOTIC INITIATION FACTOR-1 1990-2002
DeCS ID: 37529
Unique ID: D039861
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2003/01/01
Date of Entry: 2002/07/03
Revision Date: 2004/07/30
Prokaryotic Initiation Factor-1 - Preferred
Concept UI M0419356
Scope note The smallest of the three prokaryotic initiation factors with a molecular size of approximately 8 kD. It binds near the A-site of the 30S subunit of RIBOSOMES and may play a role in preventing premature addition of aminoacyl-tRNA-linked PEPTIDE ELONGATION FACTOR TU to the ribosome during the initiation of a peptide chain (PEPTIDE CHAIN INITIATION, TRANSLATIONAL).
Preferred term Prokaryotic Initiation Factor-1
Entry term(s) IF-1, Initiation Factor
Initiation Factor IF 1
Initiation Factor IF-1
Initiation Factor-1, Prokaryotic
Peptide Initiation Factor 1, Prokaryotic
Peptide Initiation Factor IF 1
Peptide Initiation Factor IF-1
Peptide Initiation Factor-1, Prokaryotic
Prokaryotic Initiation Factor 1
Prokaryotic Peptide Initiation Factor 1
Prokaryotic Peptide Initiation Factor-1



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