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Descriptor English: Prokaryotic Initiation Factor-3
Descriptor Spanish: Factor 3 Procariótico de Iniciación
Descriptor factor de iniciación procariótico 3
Entry term(s) factor IF-3 de iniciación de péptidos
Scope note: Factor procariótico de iniciación que interviene en el reciclaje de subunidades ribosómicas para un nuevo ciclo de iniciación de la traducción. Se une al ARN RIBOSÓMICO 16S y estimula la disociación de los ribosomas 70S vacantes. También puede intervenir en la unión preferente del ARNt de iniciación al complejo de iniciación 30S.
Descriptor Portuguese: Fator de Iniciação 3 em Procariotos
Descriptor French: Facteur d'initiation procaryote 3
Entry term(s): IF-3, Initiation Factor
Initiation Factor IF 3
Initiation Factor IF-3
Initiation Factor-3, Prokaryotic
Peptide Initiation Factor 3
Peptide Initiation Factor IF 3
Peptide Initiation Factor IF-3
Prokaryotic Initiation Factor 3
Prokaryotic Peptide Initiation Factor 3
Prokaryotic Peptide Initiation Factor-3
TIF IF3
Translation Initiation Factor 3
Tree number(s): D12.776.835.725.934.750
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D039665
Scope note: A prokaryotic initiation factor that plays a role in recycling of ribosomal subunits for a new round of translational initiation. It binds to 16S RIBOSOMAL RNA and stimulates the dissociation of vacant 70S ribosomes. It may also be involved in the preferential binding of initiator tRNA to the 30S initiation complex.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Peptide Initiation Factors (1979-2002)
Public MeSH Note: 2003; PEPTIDE INITIATION FACTOR 3 (now PROKARYOTIC INITIATION FACTOR-3) was indexed under PEPTIDE INITIATION FACTORS 1979-2002; TIF IF3 & TRANSLATION INITIATION FACTOR 3 were indexed under PEPTIDE INITIATION FACTORS 1994-2002
History Note: 2003; use PROKARYOTIC INITIATION FACTOR-3 (NM) 1979-2002; for TIF IF3 & TRANSLATION INITIATION FACTOR 3 use EUKARYOTIC INITIATION FACTOR-3 (NM) 1994-2002
DeCS ID: 37531
Unique ID: D039665
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2003/01/01
Date of Entry: 2002/07/03
Revision Date: 2005/07/11
Prokaryotic Initiation Factor-3 - Preferred
Concept UI M0078903
Scope note A prokaryotic initiation factor that plays a role in recycling of ribosomal subunits for a new round of translational initiation. It binds to 16S RIBOSOMAL RNA and stimulates the dissociation of vacant 70S ribosomes. It may also be involved in the preferential binding of initiator tRNA to the 30S initiation complex.
Preferred term Prokaryotic Initiation Factor-3
Entry term(s) IF-3, Initiation Factor
Initiation Factor IF 3
Initiation Factor IF-3
Initiation Factor-3, Prokaryotic
Peptide Initiation Factor 3
Peptide Initiation Factor IF 3
Peptide Initiation Factor IF-3
Prokaryotic Initiation Factor 3
Prokaryotic Peptide Initiation Factor 3
Prokaryotic Peptide Initiation Factor-3
TIF IF3
Translation Initiation Factor 3



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