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Descriptor English: Ribonuclease P
Descriptor Spanish: Ribonucleasa P
Descriptor ribonucleasa P
Entry term(s) subunidad catalítica del ARN de la ribonucleasa P
Scope note: Enzima que contiene ARN que desempeña una función esencial en el procesamiento de ARNt catalizando la escisión endonucleolítica de precursores del ARN DE TRANSFERENCIA. Elimina los 5'-nucleótidos extra de los precursores del ARNt para generar moléculas de ARNt maduras.
Descriptor Portuguese: Ribonuclease P
Descriptor French: Ribonuclease P
Entry term(s): RNA Catalytic Subunit, Ribonuclease P
RNase P
Ribonuclease P, RNA Catalytic Subunit
Tree number(s): D08.811.277.352.700.350.711
D08.811.797.500
D12.776.157.725.500.625
D12.776.664.962.500.625
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D043262
Scope note: An RNA-containing enzyme that plays an essential role in tRNA processing by catalyzing the endonucleolytic cleavage of TRANSFER RNA precursors. It removes the extra 5'-nucleotides from tRNA precursors to generate mature tRNA molecules.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.1.26.5
Previous Indexing: Endonucleases (1979-2003)
Endoribonucleases (1983-2003)
RNA, Catalytic (1991-2003)
Public MeSH Note: 2004; RIBONUCLEASE P was indexed under ENDORIBONUCLEASES 1983-2003, under RNA, CATALYTIC 1991-2003, under ENDONUCLEASES 1981-1982, & under RIBONUCLEASES 1979-1982
History Note: 2004; use RIBONUCLEASE P (NM) 1980-2003
DeCS ID: 38153
Unique ID: D043262
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2004/01/01
Date of Entry: 2003/07/09
Ribonuclease P - Preferred
Concept UI M0078728
Scope note An RNA-containing enzyme that plays an essential role in tRNA processing by catalyzing the endonucleolytic cleavage of TRANSFER RNA precursors. It removes the extra 5'-nucleotides from tRNA precursors to generate mature tRNA molecules.
Preferred term Ribonuclease P
Entry term(s) RNase P
Ribonuclease P, RNA Catalytic Subunit - Narrower
Concept UI M0445435
Preferred term Ribonuclease P, RNA Catalytic Subunit
Entry term(s) RNA Catalytic Subunit, Ribonuclease P



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