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Descriptor English: Ubiquitin-Activating Enzymes
Descriptor Spanish: Enzimas Activadoras de Ubiquitina
Descriptor enzimas activadoras de ubicuitina
Entry term(s) enzimas activadoras de la ubicuitina
enzimas activadoras de las ubicuitinas
enzimas activadoras de ubicuitinas
Scope note: Clase de enzimas que catalizan la formación dependiente del ATP de un enlace tioéster entre sí mismas y la UBICUITINA. A continuación transfieren la ubicuitina activada a una de las UBICUITINA-PROTEÍNA LIGASAS.
Descriptor Portuguese: Enzimas Ativadoras de Ubiquitina
Descriptor French: Ubiquitin-activating enzymes
Entry term(s): Enzyme E1, Ubiquitin-Activating
Enzyme, Ubiquitin-Activating
Enzymes, Ubiquitin-Activating
Ubiquitin Activating Enzyme
Ubiquitin Activating Enzyme E1
Ubiquitin Activating Enzymes
Ubiquitin-Activating Enzyme
Ubiquitin-Activating Enzyme E1
Ubiquitination Activating Enzyme E1
Tree number(s): D08.811.464.938.249
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D044764
Scope note: A class of enzymes that catalyzes the ATP-dependent formation of a thioester bond between itself and UBIQUITIN. It then transfers the activated ubiquitin to one of the UBIQUITIN-PROTEIN LIGASES.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 6.2.1.45
Previous Indexing: Ligases (1983-2003)
Public MeSH Note: 2004; UBIQUITIN-ACTIVATING ENZYME was indexed under LIGASES 1983-2003
History Note: 2004; use UBIQUITIN-ACTIVATING ENZYMES (NM) 1983-2003
DeCS ID: 38181
Unique ID: D044764
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2004/01/01
Date of Entry: 2003/07/09
Revision Date: 2016/06/02
Ubiquitin-Activating Enzymes - Preferred
Concept UI M0446165
Scope note A class of enzymes that catalyzes the ATP-dependent formation of a thioester bond between itself and UBIQUITIN. It then transfers the activated ubiquitin to one of the UBIQUITIN-PROTEIN LIGASES.
Preferred term Ubiquitin-Activating Enzymes
Entry term(s) Enzyme E1, Ubiquitin-Activating
Enzyme, Ubiquitin-Activating
Enzymes, Ubiquitin-Activating
Ubiquitin Activating Enzyme
Ubiquitin Activating Enzyme E1
Ubiquitin Activating Enzymes
Ubiquitin-Activating Enzyme
Ubiquitin-Activating Enzyme E1
Ubiquitination Activating Enzyme E1



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