| Descriptor English: | Ubiquitin-Protein Ligases | ||||||
| Descriptor Spanish: |
Ubiquitina-Proteína Ligasas
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| Descriptor Portuguese: | Ubiquitina-Proteína Ligases | ||||||
| Descriptor French: | Ubiquitin-protein ligases | ||||||
| Entry term(s): |
E3 Ligase E3 Ubiquitin Ligase Ligase E3, Ubiquitin Ligase E3, Ubiquitin-Protein Ligase, E3 Ligase, E3 Ubiquitin Ligase, Ubiquitin-Protein Ligases, Ubiquitin-Protein Ubiquitin Ligase E3 Ubiquitin Ligase, E3 Ubiquitin Protein Ligase Ubiquitin Protein Ligase E3 Ubiquitin Protein Ligases Ubiquitin-Protein Ligase Ubiquitin-Protein Ligase E3 |
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| Tree number(s): |
D08.811.464.938.750 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D044767 | ||||||
| Scope note: | A diverse class of enzymes that interact with UBIQUITIN-CONJUGATING ENZYMES and ubiquitination-specific protein substrates. Each member of this enzyme group has its own distinct specificity for a substrate and ubiquitin-conjugating enzyme. Ubiquitin-protein ligases exist as both monomeric proteins multiprotein complexes. |
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| Annotation: | UBIQUITIN-PROTEIN LIGASE COMPLEXES is also available |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 2.3.2.27 | ||||||
| Previous Indexing: |
Ligases (1983-2003) |
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| Public MeSH Note: | 2004; UBIQUITIN-PROTEIN LIGASE was indexed under LIGASES 1983-2003; E3 UBIQUITIN LIGASE was indexed under LIGASES 1993-2003 |
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| History Note: | 2004; use UBIQUITIN-PROTEIN LIGASE (NM) 1983-2003 |
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| DeCS ID: | 38183 | ||||||
| Unique ID: | D044767 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2004/01/01 | ||||||
| Date of Entry: | 2003/07/09 | ||||||
| Revision Date: | 2016/06/02 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes
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Ubiquitin-Protein Ligases
- Preferred
| Concept UI |
M0446168 |
| Scope note | A diverse class of enzymes that interact with UBIQUITIN-CONJUGATING ENZYMES and ubiquitination-specific protein substrates. Each member of this enzyme group has its own distinct specificity for a substrate and ubiquitin-conjugating enzyme. Ubiquitin-protein ligases exist as both monomeric proteins multiprotein complexes. |
| Preferred term | Ubiquitin-Protein Ligases |
| Entry term(s) |
E3 Ligase E3 Ubiquitin Ligase Ligase E3, Ubiquitin Ligase E3, Ubiquitin-Protein Ligase, E3 Ligase, E3 Ubiquitin Ligase, Ubiquitin-Protein Ligases, Ubiquitin-Protein Ubiquitin Ligase E3 Ubiquitin Ligase, E3 Ubiquitin Protein Ligase Ubiquitin Protein Ligase E3 Ubiquitin Protein Ligases Ubiquitin-Protein Ligase Ubiquitin-Protein Ligase E3 |
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