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Descriptor English: MAP Kinase Kinase Kinase 1
Descriptor Spanish: Quinasa 1 de Quinasa de Quinasa MAP
Descriptor MAP cinasa cinasa cinasa 1
Entry term(s) proteína cinasa cinasa cinasa activada por mitógenos 1
proteína quinasa quinasa quinasa activada por mitógenos 1
Scope note: Una MAP cinasa cinasa cinasa de 195-kDa con un motivo de dedos de zinc con alta especificidad para QUINASAS QUINASA PAM. Se encuentra localizada en el CITOESQUELETO y puede activar diversas vías dependientes de MAP cinasa.
Descriptor Portuguese: MAP Quinase Quinase Quinase 1
Descriptor French: MAP Kinase Kinase Kinase 1
Entry term(s): MAP ERK Kinase Kinase 1
MAP3K1 Protein
MEK Kinase 1
MEKK 1 Protein Kinase
MEKK-1 Protein Kinase
MEKK1 Protein
MEKK1 Protein Kinase
Mitogen Activated Protein Kinase Kinase Kinase 1
Mitogen-Activated Protein Kinase Kinase Kinase 1
Protein Kinase, MEKK-1
Tree number(s): D08.811.913.696.620.682.700.559.100
D12.776.476.563.554.100
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D048728
Scope note: A 195-kDa zinc finger motif-containing MAP kinase kinase kinase with broad specificity for MAP KINASE KINASES. It localizes to the CYTOSKELETON and can activate a variety of MAP kinase-dependent pathways.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.7.11.25
Previous Indexing: Mitogen-Activated Protein Kinase Kinase Kinases (2004)
Protein-Serine-Threonine Kinases (1994-2004)
Public MeSH Note: 2005; MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 1 was indexed under MAP KINASE KINASE KINASES 2004 & under PROTEIN-SERINE-THREONINE KINASES 1994-2004
History Note: 2005(1994)
Related: Zinc Fingers MeSH
DeCS ID: 38713
Unique ID: D048728
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2005/01/01
Date of Entry: 2004/07/07
Revision Date: 2016/07/05
MAP Kinase Kinase Kinase 1 - Preferred
Concept UI M0233961
Scope note A 195-kDa zinc finger motif-containing MAP kinase kinase kinase with broad specificity for MAP KINASE KINASES. It localizes to the CYTOSKELETON and can activate a variety of MAP kinase-dependent pathways.
Preferred term MAP Kinase Kinase Kinase 1
Entry term(s) MAP ERK Kinase Kinase 1
MAP3K1 Protein
MEK Kinase 1
MEKK 1 Protein Kinase
MEKK-1 Protein Kinase
MEKK1 Protein
MEKK1 Protein Kinase
Mitogen Activated Protein Kinase Kinase Kinase 1
Mitogen-Activated Protein Kinase Kinase Kinase 1
Protein Kinase, MEKK-1



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