| Descriptor English: | Mitogen-Activated Protein Kinase Kinase Kinase 11 | ||||||
| Descriptor Spanish: |
Proteina Quinasa Quinasa Quinasa 11 Activada por Mitógeno
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| Descriptor Portuguese: | MAP Quinase Quinase Quinase 11 Ativada por Mitógeno | ||||||
| Descriptor French: | Without translation | ||||||
| Entry term(s): |
Mixed Lineage Kinase 3 Mixed Lineage Kinase-3 |
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| Tree number(s): |
D08.811.913.696.620.682.700.559.650 D12.776.476.563.554.650 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000097767 | ||||||
| Scope note: | A MAP kinase kinase kinase that activates the SAPK/JNK and p38/ERK SIGNAL TRANSDUCTION pathways. It has multiple interaction domains, including a Cdc42 binding motif. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 2.7.11.25 | ||||||
| Public MeSH Note: | 2024: MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 11 was indexed under MAP KINASE KINASE KINASES 2000-2023, and under PROTEIN-SERINE-THREONINE KINASES 1997-1999 |
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| History Note: | 2024 (1997) |
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| DeCS ID: | 60640 | ||||||
| Unique ID: | D000097767 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2024/01/01 | ||||||
| Date of Entry: | 2023/07/26 | ||||||
| Revision Date: | 2023/06/14 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Mitogen-Activated Protein Kinase Kinase Kinase 11
- Preferred
| Concept UI |
M0271167 |
| Scope note | A MAP kinase kinase kinase that activates the SAPK/JNK and p38/ERK SIGNAL TRANSDUCTION pathways. It has multiple interaction domains, including a Cdc42 binding motif. |
| Preferred term | Mitogen-Activated Protein Kinase Kinase Kinase 11 |
| Entry term(s) |
Mixed Lineage Kinase 3 Mixed Lineage Kinase-3 |
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