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Descriptor English: MAP Kinase Kinase Kinase 2
Descriptor Spanish: MAP Quinasa Quinasa Quinasa 2
Descriptor MAP cinasa cinasa cinasa 2
Entry term(s) MAP quinasa quinasa quinasa 2
Scope note: MAP cinasa cinasa cinasa de 70 kDa con especificidad para MAP CINASA CINASA 5. Se activa durante la respuesta celular a FACTORES DE CRECIMIENTO, estrés oxidativo y condiciones hiperosmóticas.
Descriptor Portuguese: MAP Quinase Quinase Quinase 2
Descriptor French: MAP Kinase Kinase Kinase 2
Entry term(s): MAP3K2 Protein Kinase
MEK Kinase 2
MEKK 2 Protein Kinase
MEKK-2 Protein Kinase
MEKK2 Protein
MEKK2 Protein Kinase
Protein Kinase, MAP3K2
Protein Kinase, MEKK-2
Protein Kinase, MEKK2
Tree number(s): D08.811.913.696.620.682.700.559.200
D12.776.476.563.554.200
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D048730
Scope note: A 70-kDa MAP kinase kinase kinase with specificity for MAP KINASE KINASE 5. It is activated during the cellular response to GROWTH FACTORS, oxidative stress, and hyperosmotic conditions.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.7.11.25
Previous Indexing: MAP Kinase Kinase Kinases (1999-2004)
Public MeSH Note: 2005; MAP KINASE KINASE KINASE 2 was indexed under MAP KINASE KINASE KINASES 1999-2004
History Note: 2005(1999)
DeCS ID: 38714
Unique ID: D048730
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2005/01/01
Date of Entry: 2004/07/07
Revision Date: 2015/11/24
MAP Kinase Kinase Kinase 2 - Preferred
Concept UI M0350337
Scope note A 70-kDa MAP kinase kinase kinase with specificity for MAP KINASE KINASE 5. It is activated during the cellular response to GROWTH FACTORS, oxidative stress, and hyperosmotic conditions.
Preferred term MAP Kinase Kinase Kinase 2
Entry term(s) MAP3K2 Protein Kinase
MEK Kinase 2
MEKK 2 Protein Kinase
MEKK-2 Protein Kinase
MEKK2 Protein
MEKK2 Protein Kinase
Protein Kinase, MAP3K2
Protein Kinase, MEKK-2
Protein Kinase, MEKK2



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