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Descriptor English: p38 Mitogen-Activated Protein Kinases
Descriptor Spanish: Proteínas Quinasas p38 Activadas por Mitógenos
Descriptor proteínas cinasas p38 activadas por mitógenos
Entry term(s) proteína cinasa p38 activada por mitógenos
proteína quinasas p38 activadas por mitógenos
proteína-cinasa activada por el mitógeno p38
Scope note: Subfamilia de proteína cinasas activadas por mitógenos que regulan diversos procesos celulares como los PROCESOS DEL CRECIMIENTO CELULAR, la DIFERENCIACIÓN CELULAR, la APOPTOSIS y las respuestas celulares a la INFLAMACIÓN. Las MAP cinasas P38 son reguladas por RECEPTORES DE CITOCINAS y pueden ser activadas en respuesta a patógenos bacterianos.
Descriptor Portuguese: Proteínas Quinases p38 Ativadas por Mitógeno
Descriptor French: p38 Mitogen-Activated Protein Kinases
Entry term(s): MAP Kinase, p38
MAPK, p38
Mitogen Activated Protein Kinase p38
Mitogen-Activated Protein Kinase p38
Protein Kinase, p38
p38 MAP Kinase
p38 MAPK
p38 Mitogen Activated Protein Kinase
p38 Mitogen Activated Protein Kinases
p38 Mitogen-Activated Protein Kinase
p38 Protein Kinase
p38 SAPK
Tree number(s): D08.811.913.696.620.682.700.567.843
D12.776.476.563.567.843
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D048051
Scope note: A mitogen-activated protein kinase subfamily that regulates a variety of cellular processes including CELL GROWTH PROCESSES; CELL DIFFERENTIATION; APOPTOSIS; and cellular responses to INFLAMMATION. The P38 MAP kinases are regulated by CYTOKINE RECEPTORS and can be activated in response to bacterial pathogens.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.7.11.24
Previous Indexing: Ca(2+)-Calmodulin Dependent Protein Kinase (1994-2000)
Mitogen-Activated Protein Kinases (2000-2004)
Public MeSH Note: 2005; P38 MITOGEN-ACTIVATED PROTEIN KINASES was indexed under MITOGEN-ACTIVATED PROTEIN KINASES 2001-2004 & under CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE 1994-2000
History Note: 2005(1994)
DeCS ID: 38735
Unique ID: D048051
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2005/01/01
Date of Entry: 2004/07/08
Revision Date: 2020/05/27
p38 Mitogen-Activated Protein Kinases - Preferred
Concept UI M0234432
Scope note A mitogen-activated protein kinase subfamily that regulates a variety of cellular processes including CELL GROWTH PROCESSES; CELL DIFFERENTIATION; APOPTOSIS; and cellular responses to INFLAMMATION. The P38 MAP kinases are regulated by CYTOKINE RECEPTORS and can be activated in response to bacterial pathogens.
Preferred term p38 Mitogen-Activated Protein Kinases
Entry term(s) MAP Kinase, p38
MAPK, p38
Mitogen Activated Protein Kinase p38
Mitogen-Activated Protein Kinase p38
Protein Kinase, p38
p38 MAP Kinase
p38 MAPK
p38 Mitogen Activated Protein Kinase
p38 Mitogen Activated Protein Kinases
p38 Mitogen-Activated Protein Kinase
p38 Protein Kinase
p38 SAPK



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