| Descriptor English: | Mitogen-Activated Protein Kinase 14 | ||||||
| Descriptor Spanish: |
Proteína Quinasa 14 Activada por Mitógenos
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| Descriptor Portuguese: | Proteína Quinase 14 Ativada por Mitógeno | ||||||
| Descriptor French: | Mitogen-Activated Protein Kinase 14 | ||||||
| Entry term(s): |
CSAID Binding Protein CSAID-Binding Protein CSBP, Kinase Cytokine Suppressive Anti inflammatory Drug Binding Protein Cytokine Suppressive Anti-inflammatory Drug Binding Protein Kinase CSBP MAP Kinase, p38alpha MAPK14 MAPK14 Mitogen Activated Protein Kinase MAPK14 Mitogen-Activated Protein Kinase MAX Interacting Protein 2 MAX-Interacting Protein 2 Mitogen Activated Protein Kinase 14 Mxi2 Protein SAPK2a Stress activated protein kinase 2a Stress-activated protein kinase 2a p38alpha MAP Kinase p38alpha Mitogen Activated Protein Kinase p38alpha Mitogen-Activated Protein Kinase p38alphaMAPK |
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| Tree number(s): |
D08.811.913.696.620.682.700.567.843.937 D12.776.476.563.567.843.937 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D048308 | ||||||
| Scope note: | A 38-kDa mitogen-activated protein kinase that is abundantly expressed in a broad variety of cell types. It is involved in the regulation of cellular stress responses as well as the control of proliferation and survival of many cell types. The kinase activity of the enzyme is inhibited by the pyridinyl-imidazole compound SB 203580. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 2.7.11.24 | ||||||
| Previous Indexing: |
Ca(2+)-Calmodulin Dependent Protein Kinase (1995-1999) Mitogen-Activated Protein Kinases (2000-2004) |
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| Public MeSH Note: | 2005; MITOGEN-ACTIVATED PROTEIN KINASE 14 was indexed under MITOGEN-ACTIVATED PROTEIN KINASES 2002-2004; CSAID-BINDING PROTEIN & KINASE CSBP were indexed under MITOGEN-ACTIVATED PROTEIN KINASES 2000-2004; MXI2 PROTEIN was indexed under MITOGEN-ACTIVATED PROTEIN KINASES 2000-2004, under CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE 1994-2000 |
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| History Note: | 2005(1994) |
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| DeCS ID: | 38750 | ||||||
| Unique ID: | D048308 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2005/01/01 | ||||||
| Date of Entry: | 2004/07/07 | ||||||
| Revision Date: | 2015/11/24 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Mitogen-Activated Protein Kinase 14
- Preferred
| Concept UI |
M0417034 |
| Scope note | A 38-kDa mitogen-activated protein kinase that is abundantly expressed in a broad variety of cell types. It is involved in the regulation of cellular stress responses as well as the control of proliferation and survival of many cell types. The kinase activity of the enzyme is inhibited by the pyridinyl-imidazole compound SB 203580. |
| Preferred term | Mitogen-Activated Protein Kinase 14 |
| Entry term(s) |
CSAID Binding Protein CSAID-Binding Protein CSBP, Kinase Cytokine Suppressive Anti inflammatory Drug Binding Protein Cytokine Suppressive Anti-inflammatory Drug Binding Protein Kinase CSBP MAP Kinase, p38alpha MAPK14 MAPK14 Mitogen Activated Protein Kinase MAPK14 Mitogen-Activated Protein Kinase MAX Interacting Protein 2 MAX-Interacting Protein 2 Mitogen Activated Protein Kinase 14 Mxi2 Protein SAPK2a Stress activated protein kinase 2a Stress-activated protein kinase 2a p38alpha MAP Kinase p38alpha Mitogen Activated Protein Kinase p38alpha Mitogen-Activated Protein Kinase p38alphaMAPK |
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