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Descriptor English: Dextrorphan
Descriptor Spanish: Dextrorfano
Descriptor dextrorfano
Scope note: Forma dextrógira del levorfanol. Actúa como un antagonista no competitivo del receptor NMDA, entre otros efectos, y ha sido propuesto como agente neuroprotector. Es también un metabolito del DEXTROMETORFANO.
Descriptor Portuguese: Dextrorfano
Descriptor French: Dextrorphane
Entry term(s): (+-)-17-Methylmorphinan-3-ol
Tree number(s): D03.132.577.249.235
D03.605.497.260
D03.633.400.686.260
D04.615.723.795.235
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D003917
Scope note: Dextro form of levorphanol. It acts as a noncompetitive NMDA receptor antagonist, among other effects, and has been proposed as a neuroprotective agent. It is also a metabolite of DEXTROMETHORPHAN.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Excitatory Amino Acid Antagonists
Neuroprotective Agents
Registry Number: 04B7QNO9WS
CAS Type 1 Name: Morphinan-3-ol, 17-methyl-, (9alpha,13alpha,14alpha)-
Previous Indexing: Morphinans (1969-1974)
Public MeSH Note: 91; was see under MORPHINANS 1975-90; DEXTRODROMORAN & D-DROMORAN were see DEXTRORPHAN 1977-94; DESTRORPHANOLUM was see DEXTRORPHAN 1975-94
Online Note: use DEXTRORPHAN to search DEXTRODROMORAN & D-DROMORAN 1977-94 & DESTRORPHANOLUM 1975-94
History Note: 91(75); was see under MORPHINANS 1975-90; DEXTRODROMORAN & D-DROMORAN were see DEXTRORPHAN 1977-94; DESTRORPHANOLUM was see DEXTRORPHAN 1975-94
DeCS ID: 3938
Unique ID: D003917
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/27
Revision Date: 2016/05/29
Dextrorphan - Preferred
Concept UI M0006143
Scope note Dextro form of levorphanol. It acts as a noncompetitive NMDA receptor antagonist, among other effects, and has been proposed as a neuroprotective agent. It is also a metabolite of DEXTROMETHORPHAN.
Preferred term Dextrorphan
Entry term(s) (+-)-17-Methylmorphinan-3-ol



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