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Descriptor English: Epidermal Growth Factor
Descriptor Spanish: Factor de Crecimiento Epidérmico
Descriptor factor de crecimiento epidérmico
Entry term(s) EGF
FCE
factor de crecimiento epidérmico-urogastrona
urogastrona
Scope note: Factor de crecimiento polipeptídico de 6 kDa descubierto inicialmente en las glándulas submaxilares del ratón. Originalmente el factor de crecimiento epidérmico se aisló de la orina; por esto, y por su capacidad para inhibir la secreción gástrica, se lo denominó urogastrona. El FACTOR DE CRECIMIENTO EPIDÉRMICO tiene una gran variedad de efectos biológicos, como la promoción de la proliferación y diferenciación de células mesenquimatosas y epiteliales. Se sintetiza como proteína transmembranaria que pude ser desdoblada para liberar una forma activa soluble.
Descriptor Portuguese: Fator de Crescimento Epidérmico
Descriptor French: Facteur de croissance épidermique
Entry term(s): EGF (Epidermal Growth Factor)
Facteur de croissance de l'épiderme
HUGI
Human urinary gastric inhibitor
Urogastrone
Urogastrone bêta
bêta-Urogastrone
Tree number(s): D06.472.317.350
D12.644.276.382.500
D12.776.467.382.500
D23.529.382.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D004815
Scope note: A 6-kDa polypeptide growth factor initially discovered in mouse submaxillary glands. Human epidermal growth factor was originally isolated from urine based on its ability to inhibit gastric secretion and called urogastrone. Epidermal growth factor exerts a wide variety of biological effects including the promotion of proliferation and differentiation of mesenchymal and EPITHELIAL CELLS. It is synthesized as a transmembrane protein which can be cleaved to release a soluble active form.
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BI biosynthèse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
DE effets des médicaments et des substances chimiques
DF déficit
EC économie
GE génétique
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PH physiologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Registry Number: 62229-50-9
CAS Type 1 Name: Epidermal growth factor
Related: Agents gastro-intestinaux MeSH
Antiulcéreux MeSH
Récepteurs ErbB MeSH
DeCS ID: 4896
Unique ID: D004815
NLM Classification: WK 170
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1982/01/01
Date of Entry: 1976/04/16
Revision Date: 2018/07/02
Facteur de croissance épidermique - Preferred
Concept UI M0007549
Preferred term Facteur de croissance épidermique
Entry term(s) EGF (Epidermal Growth Factor)
Facteur de croissance de l'épiderme
HUGI
Human urinary gastric inhibitor
Urogastrone
Urogastrone bêta
bêta-Urogastrone



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