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Descriptor English: Amphiregulin
Descriptor Spanish: Anfirregulina
Descriptor anfirregulina
Scope note: Factor de crecimiento autocrino y mitógeno para una amplia gama de células diana, incluyendo las CÉLULAS EPITELIALES, FIBROBLASTOS y células del sistema inmunitario. Se presenta como proteína de membrana que puede ser escindida liberando así una forma secretora activa.
Descriptor Portuguese: Anfirregulina
Descriptor French: Amphiréguline
Entry term(s): Schwannoma derived Growth Factor
Schwannoma-derived Growth Factor
Tree number(s): D12.644.276.382.249
D12.776.467.382.249
D12.776.543.029
D23.529.382.249
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D066258
Scope note: An autocrine growth factor and mitogen for a broad range of target cells including EPITHELIAL CELLS; FIBROBLASTS and immune cells. It occurs as a membrane-bound protein that can be cleaved to release an active secreted form.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Public MeSH Note: 2015; AMPHIREGULIN was indexed under INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS 1988-2014
History Note: 2015
DeCS ID: 55618
Unique ID: D066258
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2015/01/01
Date of Entry: 2014/06/26
Revision Date: 2016/04/18
Amphiregulin - Preferred
Concept UI M0593432
Scope note An autocrine growth factor and mitogen for a broad range of target cells including EPITHELIAL CELLS; FIBROBLASTS and immune cells. It occurs as a membrane-bound protein that can be cleaved to release an active secreted form.
Preferred term Amphiregulin
Entry term(s) Schwannoma derived Growth Factor
Schwannoma-derived Growth Factor



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