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Descriptor English: bcl-2 Homologous Antagonist-Killer Protein
Descriptor Spanish: Proteína Destructora del Antagonista Homólogo bcl-2
Descriptor proteína lítica del antagonista homólogo bcl-2
Entry term(s) proteína Bak
proteína destructora del antagonista homólogo bcl-2
Scope note: Proteína de la membrana mitocondrial con multidominios y miembro de la familia de proteínas bcl-2. La proteína Bak interactúa con la PROTEÍNA P53 SUPRESORA DE TUMORES y promueve la APOPTOSIS.
Descriptor Portuguese: Proteína Killer-Antagonista Homóloga a bcl-2
Descriptor French: Protéine Bak
Entry term(s): Bak Protein
N-Bak Protein
bcl 2 Homologous Antagonist Killer Protein
bcl2 Homologous Antagonist Killer Protein
bcl2 Homologous Antagonist-Killer Protein
Tree number(s): D12.644.360.075.718.750
D12.776.476.075.718.425
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D050998
Scope note: A multi-domain mitochondrial membrane protein and member of the bcl-2 Protein family. Bak protein interacts with TUMOR SUPPRESSOR PROTEIN P53 and promotes APOPTOSIS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2006; BAK PROTEIN was indexed under MEMBRANE PROTEINS 1994-2005, & under PROTO-ONCOGENE PROTEINS 2005
History Note: 2006(1995)
DeCS ID: 50807
Unique ID: D050998
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
bcl-2 Homologous Antagonist-Killer Protein - Preferred
Concept UI M0245556
Scope note A multi-domain mitochondrial membrane protein and member of the bcl-2 Protein family. Bak protein interacts with TUMOR SUPPRESSOR PROTEIN P53 and promotes APOPTOSIS.
Preferred term bcl-2 Homologous Antagonist-Killer Protein
Entry term(s) Bak Protein
bcl 2 Homologous Antagonist Killer Protein
bcl2 Homologous Antagonist Killer Protein
bcl2 Homologous Antagonist-Killer Protein
N-Bak Protein - Narrower
Concept UI M0478941
Scope note An isoform of Bak protein containing only the N-terminal BH3 domain. N-Bak promotes neuronal apoptosis.
Preferred term N-Bak Protein



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