| Descriptor English: | Tumor Suppressor Protein p53 | ||||||
| Descriptor Spanish: |
Proteína p53 Supresora de Tumor
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| Descriptor Portuguese: | Proteína Supressora de Tumor p53 | ||||||
| Descriptor French: | Protéine p53 suppresseur de tumeur | ||||||
| Entry term(s): |
Cellular Tumor Antigen p53 Oncoprotein p53 Phosphoprotein, pp53 TP53 Protein TRP53 Protein p53 Antigen p53 Tumor Suppressor Protein pp53 Phosphoprotein |
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| Tree number(s): |
D12.776.157.687.650 D12.776.260.820 D12.776.624.776.775 D12.776.660.720.650 D12.776.744.845 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D016159 | ||||||
| Scope note: | Nuclear phosphoprotein encoded by the p53 gene (GENES, P53) whose normal function is to control CELL PROLIFERATION and APOPTOSIS. A mutant or absent p53 protein has been found in LEUKEMIA; OSTEOSARCOMA; LUNG CANCER; and COLORECTAL CANCER. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Previous Indexing: |
Neoplasm Proteins (1981-1989) Oncogene Products (1990) Phosphoproteins (1981-1990) |
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| Public MeSH Note: | 2005; see TP53 PROTEIN 1991-2005; TP53 PROTEIN was indexed under NERVE TISSUE PROTEINS & NEOPLASM PROTEINS 1992-1993 |
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| History Note: | 2005(1991); |
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| DeCS ID: | 29089 | ||||||
| Unique ID: | D016159 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1991/01/01 | ||||||
| Date of Entry: | 1990/06/19 | ||||||
| Revision Date: | 2017/05/24 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Tumor Suppressor Protein p53
- Preferred
| Concept UI |
M0024670 |
| Scope note | Nuclear phosphoprotein encoded by the p53 gene (GENES, P53) whose normal function is to control CELL PROLIFERATION and APOPTOSIS. A mutant or absent p53 protein has been found in LEUKEMIA; OSTEOSARCOMA; LUNG CANCER; and COLORECTAL CANCER. |
| Preferred term | Tumor Suppressor Protein p53 |
| Entry term(s) |
Cellular Tumor Antigen p53 Oncoprotein p53 Phosphoprotein, pp53 TP53 Protein TRP53 Protein p53 Antigen p53 Tumor Suppressor Protein pp53 Phosphoprotein |
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