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Descriptor English: Complement C5 Convertase, Alternative Pathway
Descriptor Spanish: C5 Convertasa de la Vía Alternativa del Complemento
Descriptor convertasa del complemento C5 de la vía alternativa
Scope note: Serina proteasa que desdobla el COMPLEMENTO C5 múltiple en COMPLEMENTO C5a (anafilatoxina) y COMPLEMENTO C5B en la VÍA ALTERNATIVA DE ACTIVACIÓN DEL COMPLEMENTO. Es el complejo de la C3 CONVERTASA DE LA VÍA ALTERNATIVA (C3bBb) con un COMPLEMENTO C3B, o C3bBb3b, adicional.
Descriptor Portuguese: C5 Convertase da Via Alternativa do Complemento
Descriptor French: Alternative pathway C5 convertase
Entry term(s): Alternative Pathway C5 Convertase
C5 Convertase (C3bBb3b)
C5 Convertase, Alternative Pathway
Tree number(s): D12.776.124.486.274.045.387.500.750
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D051566
Scope note: A serine protease that cleaves multiple COMPLEMENT C5 into COMPLEMENT C5A (anaphylatoxin) and COMPLEMENT C5B in the ALTERNATIVE COMPLEMENT ACTIVATION PATHWAY. It is the complex of ALTERNATIVE PATHWAY C3 CONVERTASE (C3bBb) with an additional COMPLEMENT C3B, or C3bBb3b.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Pharm Action: Immunologic Factors
Registry Number: EC 3.4.21.47
Previous Indexing: Complement Activating Enzymes (1978-2005)
Complement C5 (1976-2005)
Public MeSH Note: 2006
History Note: 2006
DeCS ID: 50831
Unique ID: D051566
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2006/07/05
Complement C5 Convertase, Alternative Pathway - Preferred
Concept UI M0476519
Scope note A serine protease that cleaves multiple COMPLEMENT C5 into COMPLEMENT C5A (anaphylatoxin) and COMPLEMENT C5B in the ALTERNATIVE COMPLEMENT ACTIVATION PATHWAY. It is the complex of ALTERNATIVE PATHWAY C3 CONVERTASE (C3bBb) with an additional COMPLEMENT C3B, or C3bBb3b.
Preferred term Complement C5 Convertase, Alternative Pathway
Entry term(s) Alternative Pathway C5 Convertase
C5 Convertase (C3bBb3b)
C5 Convertase, Alternative Pathway



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