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Descriptor English: NF-E2-Related Factor 2
Descriptor Spanish: Factor 2 Relacionado con NF-E2
Descriptor factor 2 relacionado con NF-E2
Scope note: Factor de transcripción bZIP que, en un principio, se describió como un regulador transcripcional que controlaba la expresión del gen de la BETA-GLOBINA. Este factor puede regular la expresión de una amplia variedad de genes que favorecen la protección celular frente a los daños oxidativos.
Descriptor Portuguese: Fator 2 Relacionado a NF-E2
Descriptor French: Facteur-2 apparenté à NF-E2
Entry term(s): NF E2 Related Factor 2
Nfe2l2 Protein
Nuclear Factor (Erythroid-Derived 2)-Like 2 Protein
Nuclear Factor E2 Related Factor 2
Nuclear Factor E2-Related Factor 2
Tree number(s): D12.776.260.108.737
D12.776.930.127.737
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D051267
Scope note: A basic-leucine zipper transcription factor that was originally described as a transcriptional regulator controlling expression of the BETA-GLOBIN gene. It may regulate the expression of a wide variety of genes that play a role in protecting cells from oxidative damage.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2006; NF-E2-RELATED FACTOR 2 was indexed under DNA-BINDING PROTEINS & TRANS-ACTIVATORS 1994-2005
History Note: 2006(1994)
Related: Antioxidant Response Elements MeSH
DeCS ID: 50976
Unique ID: D051267
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2012/07/03
NF-E2-Related Factor 2 - Preferred
Concept UI M0237441
Scope note A basic-leucine zipper transcription factor that was originally described as a transcriptional regulator controlling expression of the BETA-GLOBIN gene. It may regulate the expression of a wide variety of genes that play a role in protecting cells from oxidative damage.
Preferred term NF-E2-Related Factor 2
Entry term(s) NF E2 Related Factor 2
Nfe2l2 Protein
Nuclear Factor (Erythroid-Derived 2)-Like 2 Protein
Nuclear Factor E2 Related Factor 2
Nuclear Factor E2-Related Factor 2



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