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Descriptor English: Interferon Regulatory Factor-1
Descriptor Spanish: Factor 1 Regulador del Interferón
Descriptor factor 1 regulador del interferón
Entry term(s) factor de transcripción IRF-1
Scope note: Factor regulador del interferón que se une a ELEMENTOS REGULADORES DE LA TRANSCRIPCIÓN hacia 5' en los GENES para el INTEFERÓN ALFA y el INTERFERÓN BETA. Funciona como activador transcripcional para los genes del INTERFERÓN DE TIPO I.
Descriptor Portuguese: Fator Regulador 1 de Interferon
Descriptor French: Facteur-1 de régulation d'interféron
Entry term(s): Factor, IRF-1 Transcription
Factor, ISGF1 Transcription
IREBF1 Protein
IREBF1 Transcription Factor
IRF 1 Protein
IRF 1 Transcription Factor
IRF-1 Protein
IRF-1 Transcription Factor
ISGF1 Transcription Factor
Interferon Regulatory Factor 1
Interferon Stimulated Gene Factor 1
Interferon-Stimulated Gene Factor 1
MyD32 Protein
Transcription Factor, IREBF1
Transcription Factor, IRF-1
Transcription Factor, ISGF1
Tree number(s): D12.644.360.024.302.124
D12.776.157.057.050.124
D12.776.260.108.374
D12.776.260.504.124
D12.776.476.024.385.124
D12.776.930.127.374
D12.776.930.332.124
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D050856
Scope note: An interferon regulatory factor that binds upstream TRANSCRIPTIONAL REGULATORY ELEMENTS in the GENES for INTERFERON-ALPHA and INTERFERON-BETA. It functions as a transcriptional activator for the INTERFERON TYPE I genes.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2006; INTERFERON REGULATORY FACTOR was indexed under DNA-BINDING PROTEINS 1990-2005; PHOSPHOPROTEINS 1990-2005; & PROTEINS 1989
History Note: 2006(1989)
DeCS ID: 50775
Unique ID: D050856
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2015/11/23
Interferon Regulatory Factor-1 - Preferred
Concept UI M0166190
Scope note An interferon regulatory factor that binds upstream TRANSCRIPTIONAL REGULATORY ELEMENTS in the GENES for INTERFERON-ALPHA and INTERFERON-BETA. It functions as a transcriptional activator for the INTERFERON TYPE I genes.
Preferred term Interferon Regulatory Factor-1
Entry term(s) Factor, IRF-1 Transcription
Factor, ISGF1 Transcription
IREBF1 Protein
IREBF1 Transcription Factor
IRF 1 Protein
IRF 1 Transcription Factor
IRF-1 Protein
IRF-1 Transcription Factor
ISGF1 Transcription Factor
Interferon Regulatory Factor 1
Interferon Stimulated Gene Factor 1
Interferon-Stimulated Gene Factor 1
MyD32 Protein
Transcription Factor, IREBF1
Transcription Factor, IRF-1
Transcription Factor, ISGF1



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