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Descriptor English: Activating Transcription Factors
Descriptor Spanish: Factores de Transcripción Activadores
Descriptor factores de transcripción activadores
Scope note: Los factores de transcripción activadores se identificaron originalmente como PROTEÍNAS DE UNIÓN AL ADN que interactúan con los PROMOTORES TEMPRANOS de los ADENOVIRUS. Son una familia de factores de transcripción de cremallera de leucina básica que se unen al sitio de consenso TGACGTCA del elemento de respuesta del AMP cíclico y se hallan estrechamente relacionados con la PROTEÍNA DE UNIÓN AL ADN SENSIBLE AL AMP CÍCLICO.
Descriptor Portuguese: Fatores Ativadores da Transcrição
Descriptor French: Facteurs de transcription ATF
Entry term(s): ATF Transcription Factors
Factors, ATF Transcription
Transcription Factors, ATF
Tree number(s): D12.776.260.108.061
D12.776.930.127.061
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D051696
Scope note: Activating transcription factors were originally identified as DNA-BINDING PROTEINS that interact with early promoters from ADENOVIRUSES. They are a family of basic leucine zipper transcription factors that bind to the consensus site TGACGTCA of the cyclic AMP response element, and are closely related to CYCLIC AMP-RESPONSIVE DNA-BINDING PROTEIN.
Annotation: general; prefer specifics
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2006
History Note: 2006
DeCS ID: 50953
Unique ID: D051696
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2009/07/17
Activating Transcription Factors - Preferred
Concept UI M0481519
Scope note Activating transcription factors were originally identified as DNA-BINDING PROTEINS that interact with early promoters from ADENOVIRUSES. They are a family of basic leucine zipper transcription factors that bind to the consensus site TGACGTCA of the cyclic AMP response element, and are closely related to CYCLIC AMP-RESPONSIVE DNA-BINDING PROTEIN.
Preferred term Activating Transcription Factors
Entry term(s) ATF Transcription Factors
Factors, ATF Transcription
Transcription Factors, ATF



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