| Descriptor English: | alpha-Glucosidases | ||||||
| Descriptor Spanish: | 
                                alfa-Glucosidasas                                        
                                        
                                                                                                                            
                                            
  | ||||||
| Descriptor Portuguese: | alfa-Glucosidases | ||||||
| Descriptor French: | alpha-Glucosidase | ||||||
| Entry term(s): | 
                                    Acid Maltase Lysosomal alpha Glucosidase Lysosomal alpha-Glucosidase Maltase Maltase Glucoamylase Maltase-Glucoamylase Maltases Neutral Maltase Neutral alpha Glucosidase Neutral alpha-Glucosidase alpha Glucosidase alpha Glucosidases alpha-Glucosidase alpha-Glucosidase, Lysosomal alpha-Glucosidase, Neutral  | 
                                            ||||||
| Tree number(s): | 
                                        D08.811.277.450.420.050 | 
                                ||||||
| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000520 | ||||||
| Scope note: | Enzymes that catalyze the exohydrolysis of 1,4-alpha-glucosidic linkages with release of alpha-glucose. Deficiency of alpha-1,4-glucosidase may cause GLYCOGEN STORAGE DISEASE TYPE II. | 
                                    ||||||
| Annotation: | defic/: consider also GLYCOGEN STORAGE DISEASE TYPE II | 
                                    ||||||
| Allowable Qualifiers: | 
                                                                        AD                                                            administration & dosage AE adverse effects AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine  | 
                                            ||||||
| Entry Combination: | 
                                                                            antagonists & inhibitors:Glycoside Hydrolase Inhibitors
                                                                                 | 
                                        ||||||
| Registry Number: | EC 3.2.1.20 | ||||||
| CAS Type 1 Name: | alpha-D-Glucoside glucohydrolases | ||||||
| Previous Indexing: | 
                                                Glucosidases (1966-1977) | 
                                        ||||||
| Public MeSH Note: | 1987; see GLUCOSIDASES 1978-1986, for LYSOSOMAL ALPHA-GLUCOSIDASE & ACID MALTASE see GLUCAN 1,4-ALPHA-GLUCOSIDASE 1978-2006 | 
                                                ||||||
| History Note: | 1987(1978) | 
                                                ||||||
| Related: | 
                                                                                                                        Glycogen Storage Disease Type II
                                            MeSH                                             | ||||||
| DeCS ID: | 520 | ||||||
| Unique ID: | D000520 | ||||||
| NLM Classification: | QU 136 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1987/01/01 | ||||||
| Date of Entry: | 1977/04/15 | ||||||
| Revision Date: | 2020/05/27 | 
- 
                                    
- 
                                        CHEMICALS AND DRUGS
 
Enzymes and Coenzymes [D08]Enzymes and Coenzymes 
| 
                                                             | 
                                
                        
                                                                    
                        alpha-Glucosidases                                            
                                        - Preferred                                        
                                                                
                                
                        
                        
                        
                                                                    
                        Lysosomal alpha-Glucosidase                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Neutral alpha-Glucosidase                                            
                                        - Narrower                                        
                                                                
                                
                        
                        
                    
                    
                
                | Concept UI | 
                                        
                                        M0000794 | 
                                
| Scope note | Enzymes that catalyze the exohydrolysis of 1,4-alpha-glucosidic linkages with release of alpha-glucose. Deficiency of alpha-1,4-glucosidase may cause GLYCOGEN STORAGE DISEASE TYPE II. | 
| Preferred term | alpha-Glucosidases | 
| Entry term(s) | 
                                        
                                                                                            Maltase                                                 Maltase Glucoamylase Maltase-Glucoamylase Maltases alpha Glucosidase alpha Glucosidases alpha-Glucosidase  | 
                                
| Concept UI | 
                                        
                                        M0497620 | 
                                
| Preferred term | Lysosomal alpha-Glucosidase | 
| Entry term(s) | 
                                        
                                                                                            Acid Maltase                                                 Lysosomal alpha Glucosidase alpha-Glucosidase, Lysosomal  | 
                                
| Concept UI | 
                                        
                                        M0000795 | 
                                
| Preferred term | Neutral alpha-Glucosidase | 
| Entry term(s) | 
                                        
                                                                                            Neutral Maltase                                                 Neutral alpha Glucosidase alpha-Glucosidase, Neutral  | 
                                
We want your feedback on the new DeCS / MeSH website
We invite you to complete a survey that will take no more than 3 minutes.
Go to survey