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Descriptor in English: Glucosylceramidase
Descriptor in Spanish: Glucosilceramidasa
Descriptor in Portuguese: Glucosilceramidase
Descriptor in French: Glucosylceramidase
Entry term(s): Acid beta Glucosidase
Acid beta-Glucosidase
Ceramidase, Glucosyl
Glucocerebrosidase
Glucocerebroside beta Glucosidase
Glucocerebroside beta-Glucosidase
Glucosyl Ceramidase
Glucosyl Hydrolase, Glucosylsphingosine
Glucosylceramide beta Glucosidase
Glucosylceramide beta-Glucosidase
Glucosylsphingosine Glucosyl Hydrolase
Hydrolase, Glucosylsphingosine Glucosyl
beta Glucocerebrosidase
beta-Glucocerebrosidase
beta-Glucosidase, Acid
beta-Glucosidase, Glucocerebroside
beta-Glucosidase, Glucosylceramide
Tree number(s): D08.811.277.450.420.412
Scope note: A glycosidase that hydrolyzes a glucosylceramide to yield free ceramide plus glucose. Deficiency of this enzyme leads to abnormally high concentrations of glucosylceramide in the brain in GAUCHER DISEASE. EC 3.2.1.45.
Annotation: /defic: consider also GAUCHER DISEASE
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
History Note: 91(75); was see under GLUCOSIDASES 1975-90
See also the descriptors: Gaucher Disease MeSH
DeCS UI: 6107
Descriptor UI: D005962
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2013/07/08
Glucosylceramidase - Preferred
Concept UI M0009360
Scope note A glycosidase that hydrolyzes a glucosylceramide to yield free ceramide plus glucose. Deficiency of this enzyme leads to abnormally high concentrations of glucosylceramide in the brain in GAUCHER DISEASE. EC 3.2.1.45.
Preferred term Glucosylceramidase
Entry term(s) Acid beta Glucosidase
Acid beta-Glucosidase
Ceramidase, Glucosyl
Glucocerebrosidase
Glucocerebroside beta Glucosidase
Glucocerebroside beta-Glucosidase
Glucosyl Ceramidase
Glucosyl Hydrolase, Glucosylsphingosine
Glucosylceramide beta Glucosidase
Glucosylceramide beta-Glucosidase
Glucosylsphingosine Glucosyl Hydrolase
Hydrolase, Glucosylsphingosine Glucosyl
beta Glucocerebrosidase
beta-Glucocerebrosidase
beta-Glucosidase, Acid
beta-Glucosidase, Glucocerebroside
beta-Glucosidase, Glucosylceramide



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