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Descriptor English: Transforming Growth Factor beta2
Descriptor Spanish: Factor de Crecimiento Transformador beta2
Descriptor factor de crecimiento transformador beta2
Entry term(s) TGF-beta2
factor beta2 del crecimiento transformador
factor del crecimiento transformador beta-2
factor del crecimiento transformador beta2
Scope note: Subtipo de TGF-beta identificado originalmente como factor derivado de GLIOBLASTOMA que inhibe el crecimiento dependiente de antígenos de los LINFOCITOS T CITOTÓXICOS y colaboradores. Se sintetiza como molécula precursora que es desdoblada para formar TGF-beta 2 maduro y péptido asociado a latencia TGF-beta 2. La asociación de los productos de desdoblamiento da lugar a la formación de una proteína latente que debe ser activada para unirse a su receptor.
Descriptor Portuguese: Fator de Crescimento Transformador beta2
Descriptor French: Facteur de croissance transformant bêta-2
Entry term(s): BSC 1 Cell Growth Inhibitor
BSC-1 Cell Growth Inhibitor
Cartilage Inducing Factor B
Cartilage-Inducing Factor-B
Glioblastoma Derived T Cell Suppressor Factor
Glioblastoma-Derived T-Cell Suppressor Factor
Latency-Associated Protein, TGF-beta2
Polyergin
Suppressor Factor, T-Cell, Glioblastoma-Derived
TGF beta2 Latency Associated Protein
TGF beta2LAP
TGF-beta-2
TGF-beta2
TGF-beta2 Latency-Associated Protein
TGF-beta2LAP
Transforming Growth Factor beta 2 Latency Associated Peptide
Tree number(s): D12.644.276.374.687.200
D12.644.276.954.775.200
D12.776.467.374.687.200
D12.776.467.942.775.200
D23.529.374.687.200
D23.529.942.775.200
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D053781
Scope note: A TGF-beta subtype that was originally identified as a GLIOBLASTOMA-derived factor which inhibits the antigen-dependent growth of both helper and CYTOTOXIC T LYMPHOCYTES. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta2 and TGF-beta2 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2007; TRANSFORMING GROWTH FACTOR BETA2 was indexed under TRANSFROMING GROWTH FACTOR BETA 2000-2006
History Note: 2007(2000)
DeCS ID: 52286
Unique ID: D053781
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2015/06/02
Transforming Growth Factor beta2 - Preferred
Concept UI M0024759
Scope note A TGF-beta subtype that was originally identified as a GLIOBLASTOMA-derived factor which inhibits the antigen-dependent growth of both helper and CYTOTOXIC T LYMPHOCYTES. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta2 and TGF-beta2 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor.
Preferred term Transforming Growth Factor beta2
Entry term(s) BSC 1 Cell Growth Inhibitor
BSC-1 Cell Growth Inhibitor
Cartilage Inducing Factor B
Cartilage-Inducing Factor-B
Glioblastoma Derived T Cell Suppressor Factor
Glioblastoma-Derived T-Cell Suppressor Factor
Polyergin
Suppressor Factor, T-Cell, Glioblastoma-Derived
TGF-beta-2
TGF-beta2
Transforming Growth Factor beta 2 Latency Associated Peptide - Narrower
Concept UI M0496452
Preferred term Transforming Growth Factor beta 2 Latency Associated Peptide
Entry term(s) Latency-Associated Protein, TGF-beta2
TGF beta2 Latency Associated Protein
TGF beta2LAP
TGF-beta2 Latency-Associated Protein
TGF-beta2LAP



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