| Descriptor English: | Apoptotic Protease-Activating Factor 1 | ||||||
| Descriptor Spanish: |
Factor Apoptótico 1 Activador de Proteasas
| ||||||
| Descriptor Portuguese: | Fator Apoptótico 1 Ativador de Proteases | ||||||
| Descriptor French: | Facteur-1 activateur des protéases apoptotiques | ||||||
| Entry term(s): |
Apaf 1 Protease Activating Factor Apaf-1 Protease-Activating Factor Apoptotic Peptidase Activating Factor 1 Apoptotic Protease Activating Factor 1 Protease-Activating Factor, Apaf-1 |
||||||
| Tree number(s): |
D12.644.360.024.131.124 D12.644.360.075.358.124 D12.776.157.057.006.124 D12.776.476.024.139.124 D12.776.476.075.358.124 |
||||||
| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D053477 | ||||||
| Scope note: | A CARD signaling adaptor protein characterized by an N-terminal CARD DOMAIN and C-terminal WD40 REPEATS. It plays a role in the mitochondria-stimulated apoptosis (APOPTOSIS, INTRINSIC PATHWAY) and binds to CYTOCHROME C in the CYTOSOL to form an APOPTOSOMAL PROTEIN COMPLEX which activates INITIATOR CASPASES such as CASPASE 9. |
||||||
| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
||||||
| Public MeSH Note: | 2007; APOPTOTIC PROTEASE-ACTIVATING FACTOR 1 was indexed under INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS 1997-2006 & under PROTEINS 1997-2005 |
||||||
| History Note: | 2007(1997) |
||||||
| DeCS ID: | 52304 | ||||||
| Unique ID: | D053477 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2007/01/01 | ||||||
| Date of Entry: | 2006/07/05 | ||||||
| Revision Date: | 2016/04/15 |
-
-
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
|
|
Apoptotic Protease-Activating Factor 1
- Preferred
| Concept UI |
M0279898 |
| Scope note | A CARD signaling adaptor protein characterized by an N-terminal CARD DOMAIN and C-terminal WD40 REPEATS. It plays a role in the mitochondria-stimulated apoptosis (APOPTOSIS, INTRINSIC PATHWAY) and binds to CYTOCHROME C in the CYTOSOL to form an APOPTOSOMAL PROTEIN COMPLEX which activates INITIATOR CASPASES such as CASPASE 9. |
| Preferred term | Apoptotic Protease-Activating Factor 1 |
| Entry term(s) |
Apaf 1 Protease Activating Factor Apaf-1 Protease-Activating Factor Apoptotic Peptidase Activating Factor 1 Apoptotic Protease Activating Factor 1 Protease-Activating Factor, Apaf-1 |
We want your feedback on the new DeCS / MeSH website
We invite you to complete a survey that will take no more than 3 minutes.
Go to survey
