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Descriptor English: Nod1 Signaling Adaptor Protein
Descriptor Spanish: Proteína Adaptadora de Señalización NOD1
Descriptor proteína adaptadora de señalización NOD1
Entry term(s) proteína 1 de dominio de oligomerización de nucleótidos
Scope note: Proteína adaptadora señalizadora de NOD que contiene un dominio C-terminal rico en leucina que reconoce el PEPTIDOGLICANO BACTERIANO. Señala por medio de un dominio de reclutamiento N-terminal de caspasas que interactúa con otras PROTEÍNAS ADAPTADORAS DE SEÑALIZACIÓN CARD tales como las SERINA-TREONINA CINASAS RIP. Desempeña un papel en la respuesta defensiva del huésped al señalizar la activación de CASPASAS y el SISTEMA DE SEÑALIZACIÓN MAP CINASA.
Descriptor Portuguese: Proteína Adaptadora de Sinalização NOD1
Descriptor French: Protéine adaptatrice de signalisation NOD1
Entry term(s): CARD4 Protein
Caspase Recruitment Domain Protein 4
Nucleotide Oligomerization Domain 1 Protein
Tree number(s): D12.644.360.024.131.249
D12.644.360.024.313.249
D12.644.360.075.358.249
D12.644.360.539.500.249
D12.776.157.057.006.249
D12.776.157.057.078.249
D12.776.476.024.139.249
D12.776.476.024.391.249
D12.776.476.075.358.249
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D053474
Scope note: A NOD-signaling adaptor protein that contains a C-terminal leucine-rich domain which recognizes bacterial PEPTIDOGLYCAN. It signals via an N-terminal caspase recruitment domain that interacts with other CARD SIGNALING ADAPTOR PROTEINS such as RIP SERINE-THEONINE KINASES. It plays a role in the host defense response by signaling the activation of CASPASES and the MAP KINASE SIGNALING SYSTEM.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Adaptor Proteins, Signal Transducing (2005-2006)
Carrier Proteins (1999-2004)
Public MeSH Note: 2007
History Note: 2007
DeCS ID: 52306
Unique ID: D053474
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2016/03/30
Nod1 Signaling Adaptor Protein - Preferred
Concept UI M0493409
Scope note A NOD-signaling adaptor protein that contains a C-terminal leucine-rich domain which recognizes bacterial PEPTIDOGLYCAN. It signals via an N-terminal caspase recruitment domain that interacts with other CARD SIGNALING ADAPTOR PROTEINS such as RIP SERINE-THEONINE KINASES. It plays a role in the host defense response by signaling the activation of CASPASES and the MAP KINASE SIGNALING SYSTEM.
Preferred term Nod1 Signaling Adaptor Protein
Entry term(s) CARD4 Protein
Caspase Recruitment Domain Protein 4
Nucleotide Oligomerization Domain 1 Protein



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