| Descriptor English: | Cathelicidins | ||||||
| Descriptor Spanish: | 
                                Catelicidinas                                        
                                        
                                                                                                                            
                                            
  | ||||||
| Descriptor Portuguese: | Catelicidinas | ||||||
| Descriptor French: | Cathélicidines | ||||||
| Entry term(s): | 
                                    ALL 38 Peptide ALL-38 Peptide Antibacterial Peptide LL 37 Antibacterial Peptide LL-37 Antibacterial Peptide, LL-37 Antimicrobial Peptide LL 37 Antimicrobial Peptide LL-37 Antimicrobial Peptide, Cathelin-Related Bac4 Protein, Bos taurus CAP 18 CAP-18 CAP18 CAP18 Lipopolysaccharide Binding Protein CAP18 Lipopolysaccharide-Binding Protein CATH 1 Protein CATH-1 Protein Cathelicidin Cathelicidin 1 Cathelicidin Antimicrobial Peptide Cathelicidin LL 37 Cathelicidin LL-37 Cathelicidin-1 Cathelin-Like Protein Cathelin-Related Antimicrobial Peptide FA LL 37 FA-LL-37 K9CATH LL 37 Antibacterial Peptide LL 37 Peptide LL-37 Antibacterial Peptide LL-37 Peptide LL-37, Antibacterial Peptide LL-37, Antimicrobial Peptide LL-37, Cathelicidin Lipopolysaccharide-Binding Protein, CAP18 Myeloid Cathelicidin 1 Protein, Equus caballus Peptide LL-37, Antibacterial Peptide LL-37, Antimicrobial Peptide, ALL-38 Peptide, Cathelin-Related Antimicrobial Peptide, LL-37 Peptide, LL-37 Antibacterial Protein, CAP18 Lipopolysaccharide-Binding Protein, CATH-1 Protein, Cathelin-Like Ropocamptide eCATH 1 eCATH 1 protein, Equus caballus eCATH-1 eCATH-1 protein, Equus caballus hCAP 18 hCAP-18  | 
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| Tree number(s): | 
                                        D12.644.050.099 D12.644.066.500.099 D12.776.543.695.054.099  | 
                                ||||||
| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D054804 | ||||||
| Scope note: | Antimicrobial cationic peptides with a highly conserved amino terminal cathelin-like domain and a more variable carboxy terminal domain. They are initially synthesized as preproproteins and then cleaved. They are expressed in many tissues of humans and localized to EPITHELIAL CELLS. They kill nonviral pathogens by forming pores in membranes. | 
                                    ||||||
| Allowable Qualifiers: | 
                                                                        AD                                                            administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine  | 
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| Public MeSH Note: | 2008 | 
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| History Note: | 2008 | 
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| DeCS ID: | 52752 | ||||||
| Unique ID: | D054804 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2008/01/01 | ||||||
| Date of Entry: | 2007/07/09 | ||||||
| Revision Date: | 2022/07/14 | 
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                                        CHEMICALS AND DRUGS
 
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins - 
                                    
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins - 
                                    
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins 
| 
                                                             | 
                                
                        
                                                                    
                        Cathelicidins                                            
                                        - Preferred                                        
                                                                
                                
                        
                        
                        
                                                                    
                        K9CATH                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Cathelin-Like Protein                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Cathelin-Related Antimicrobial Peptide                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        eCATH-1                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        hCAP-18                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Cathelicidin 1                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        CAP-18                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Bac4 Protein, Bos taurus                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        eCATH-1 protein, Equus caballus                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        ALL-38 Peptide                                            
                                        - Narrower                                        
                                                                
                                
                        
                        
                    
                    
                
                | Concept UI | 
                                        
                                        M0507778 | 
                                
| Scope note | Antimicrobial cationic peptides with a highly conserved amino terminal cathelin-like domain and a more variable carboxy terminal domain. They are initially synthesized as preproproteins and then cleaved. They are expressed in many tissues of humans and localized to EPITHELIAL CELLS. They kill nonviral pathogens by forming pores in membranes. | 
| Preferred term | Cathelicidins | 
| Entry term(s) | 
                                        
                                                                                            Cathelicidin                                                 Cathelicidin Antimicrobial Peptide  | 
                                
| Concept UI | 
                                        
                                        M000646653 | 
                                
| Preferred term | K9CATH | 
| Concept UI | 
                                        
                                        M000751382 | 
                                
| Preferred term | Cathelin-Like Protein | 
| Entry term(s) | 
                                        
                                                                                            Protein, Cathelin-Like                                                 | 
                                
| Concept UI | 
                                        
                                        M000751383 | 
                                
| Preferred term | Cathelin-Related Antimicrobial Peptide | 
| Entry term(s) | 
                                        
                                                                                            Antimicrobial Peptide, Cathelin-Related                                                 Peptide, Cathelin-Related Antimicrobial  | 
                                
| Concept UI | 
                                        
                                        M000751384 | 
                                
| Preferred term | eCATH-1 | 
| Entry term(s) | 
                                        
                                                                                            eCATH 1                                                 | 
                                
| Concept UI | 
                                        
                                        M000751385 | 
                                
| Preferred term | hCAP-18 | 
| Entry term(s) | 
                                        
                                                                                            hCAP 18                                                 | 
                                
| Concept UI | 
                                        
                                        M000757336 | 
                                
| Preferred term | Cathelicidin 1 | 
| Entry term(s) | 
                                        
                                                                                            Cathelicidin-1                                                 | 
                                
| Concept UI | 
                                        
                                        M0192257 | 
                                
| Preferred term | CAP-18 | 
| Entry term(s) | 
                                        
                                                                                            Antibacterial Peptide LL 37                                                 Antibacterial Peptide LL-37 Antibacterial Peptide, LL-37 Antimicrobial Peptide LL 37 Antimicrobial Peptide LL-37 CAP 18 CAP18 CAP18 Lipopolysaccharide Binding Protein CAP18 Lipopolysaccharide-Binding Protein Cathelicidin LL 37 Cathelicidin LL-37 FA LL 37 FA-LL-37 LL 37 Antibacterial Peptide LL 37 Peptide LL-37 Antibacterial Peptide LL-37 Peptide LL-37, Antibacterial Peptide LL-37, Antimicrobial Peptide LL-37, Cathelicidin Lipopolysaccharide-Binding Protein, CAP18 Peptide LL-37, Antibacterial Peptide LL-37, Antimicrobial Peptide, LL-37 Peptide, LL-37 Antibacterial Protein, CAP18 Lipopolysaccharide-Binding Ropocamptide  | 
                                
| Concept UI | 
                                        
                                        M0286449 | 
                                
| Preferred term | Bac4 Protein, Bos taurus | 
| Concept UI | 
                                        
                                        M0366472 | 
                                
| Preferred term | eCATH-1 protein, Equus caballus | 
| Entry term(s) | 
                                        
                                                                                            CATH 1 Protein                                                 CATH-1 Protein Myeloid Cathelicidin 1 Protein, Equus caballus Protein, CATH-1 eCATH 1 protein, Equus caballus  | 
                                
| Concept UI | 
                                        
                                        M0453506 | 
                                
| Preferred term | ALL-38 Peptide | 
| Entry term(s) | 
                                        
                                                                                            ALL 38 Peptide                                                 Peptide, ALL-38  | 
                                
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