DeCS

Descriptor English:

Antimicrobial Cationic Peptides

Descriptor Spanish:

Péptidos Catiónicos Antimicrobianos

Spanish from Spain

Descriptor	péptidos catiónicos antimicrobianos
Entry term(s)	proteínas catiónicas microbicidas péptido catiónico antimicrobiano péptido de defensa del huésped péptidos antimicrobianos catiónicos péptidos catiónicos de defensa del huésped péptidos de defensa del huésped
Scope note:	Pequeños péptidos catiónicos que son un componente importante, en la mayoría de las especies, de las defensas innatas e inducidas frente a los microbios invasores. En los animales se encuentran en las mucosas, dentro de los gránulos fagocíticos, y en la superficie del cuerpo. También se encuentran en insectos y plantas. Este grupo incluye, entre otras, las DEFENSINAS, protegrinas, taquiplesinas y tioninas. Desplazan CATIONES DIVALENTES de los grupos fosfato de los LÍPIDOS DE MEMBRANA, lo que lleva a rotura de la membrana.

Descriptor Portuguese:

Peptídeos Catiônicos Antimicrobianos

Descriptor French:

Peptides antimicrobiens cationiques

Entry term(s):

Amphipathic Cationic Antimicrobial Peptides
Antimicrobial Peptides, Cationic
Cationic Antimicrobial Peptide
Cationic Antimicrobial Peptides
Cationic Host Defense Peptides
Cationic Peptides, Antimicrobial
Cationic Proteins, Microbicidal
Defense Peptide, Host
Defense Peptides, Host
Host Defense Peptide
Host Defense Peptides
Microbicidal Cationic Proteins
Peptide, Host Defense
Peptides, Antimicrobial Cationic
Peptides, Cationic Antimicrobial
Peptides, Host Defense
Proteins, Microbicidal Cationic

Tree number(s):

D12.644.050
D12.644.066.500
D12.776.543.695.054

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D023181

Scope note:

Small cationic peptides that are an important component, in most species, of early innate and induced defenses against invading microbes. In animals they are found on mucosal surfaces, within phagocytic granules, and on the surface of the body. They are also found in insects and plants. Among others, this group includes the DEFENSINS, protegrins, tachyplesins, and thionins. They displace DIVALENT CATIONS from phosphate groups of MEMBRANE LIPIDS leading to disruption of the membrane.

Allowable Qualifiers:

AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine

Concept UI	M0093656
Scope note	Small cationic peptides that are an important component, in most species, of early innate and induced defenses against invading microbes. In animals they are found on mucosal surfaces, within phagocytic granules, and on the surface of the body. They are also found in insects and plants. Among others, this group includes the DEFENSINS, protegrins, tachyplesins, and thionins. They displace DIVALENT CATIONS from phosphate groups of MEMBRANE LIPIDS leading to disruption of the membrane.
Preferred term	Antimicrobial Cationic Peptides
Entry term(s)	Antimicrobial Peptides, Cationic Cationic Antimicrobial Peptide Cationic Antimicrobial Peptides Cationic Host Defense Peptides Cationic Peptides, Antimicrobial Cationic Proteins, Microbicidal Microbicidal Cationic Proteins Peptides, Antimicrobial Cationic Peptides, Cationic Antimicrobial Proteins, Microbicidal Cationic

Concept UI	M0507776
Preferred term	Amphipathic Cationic Antimicrobial Peptides

Concept UI	M000745106
Preferred term	Host Defense Peptides
Entry term(s)	Defense Peptide, Host Defense Peptides, Host Host Defense Peptide Peptide, Host Defense Peptides, Host Defense

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