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Descriptor English: Nucleoplasmins
Descriptor Spanish: Nucleoplasminas
Descriptor nucleoplasminas
Scope note: Familia de chaperonas moleculares de histonas que desempeñan papeles en la descondensación de la CROMATINA del esperma y en el ENSAMBLAJE DE LA CROMATINA en los huevos fertilizados. Fueron descubiertas originalmente en extractos de huevos de XENOPUS como factores de unión a histonas que mediaban en la formación de nucleosomas in vitro.
Descriptor Portuguese: Nucleoplasminas
Descriptor French: Nucléoplasmines
Entry term(s): Nucleoplasmin
Tree number(s): D12.776.580.219.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D056489
Scope note: A family of histone molecular chaperones that play roles in sperm CHROMATIN decondensation and CHROMATIN ASSEMBLY in fertilized eggs. They were originally discovered in XENOPUS egg extracts as histone-binding factors that mediate nucleosome formation in vitro.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2010
History Note: 2010
DeCS ID: 53654
Unique ID: D056489
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2010/01/01
Date of Entry: 2009/07/06
Nucleoplasmins - Preferred
Concept UI M0527497
Scope note A family of histone molecular chaperones that play roles in sperm CHROMATIN decondensation and CHROMATIN ASSEMBLY in fertilized eggs. They were originally discovered in XENOPUS egg extracts as histone-binding factors that mediate nucleosome formation in vitro.
Preferred term Nucleoplasmins
Entry term(s) Nucleoplasmin



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