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Descriptor English: Chromatin Assembly Factor-1
Descriptor Spanish: Factor 1 de Ensamblaje de la Cromatina
Descriptor factor 1 del ensamblaje de cromatina
Scope note: Proteína chaperona de histonas que desempeña un papel en la sedimentación de NUCLEOSOMAS sobre el ADN recién sintetizado. Está compuesto de tres subunidades diferentes de tamaño molecular de 48, 60 y 150 kDa. La subunidad de 48 kDa, PROTEÍNA 4 DE UNIÓN AL RETINOBLASTOMA, es también un componente de otros diversos complejos de proteínas implicados en la remodelación de la cromatina.
Descriptor Portuguese: Fator 1 de Modelagem da Cromatina
Descriptor French: Facteur-1 d'assemblage de la chromatine
Entry term(s): Assembly Complex-1, Chromatin
Assembly Factor-1, Chromatin
Chromatin Assembly Complex 1
Chromatin Assembly Complex 1, p150 Subunit
Chromatin Assembly Complex 1, p60 Subunit
Chromatin Assembly Complex-1
Chromatin Assembly Complex-1, p150 Subunit
Chromatin Assembly Complex-1, p60 Subunit
Chromatin Assembly Factor 1
Tree number(s): D12.776.580.219.200
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D056504
Scope note: A histone chaperone protein that plays a role in the deposition of NUCLEOSOMES on newly synthesized DNA. It is comprised of three different subunits of 48, 60, and 150 kDa molecular size. The 48 kDa subunit, RETINOBLASTOMA-BINDING PROTEIN 4, is also a component of several other protein complexes involved in chromatin remodeling.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2010; CHROMATIN ASSEMBLY FACTOR-1 was indexed under CHROMOSOMAL PROTEINS, NON-HISTONE and DNA-BINDING PROTEINS 1995-2009
History Note: 2010(1995)
DeCS ID: 53653
Unique ID: D056504
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2010/01/01
Date of Entry: 2009/07/06
Chromatin Assembly Factor-1 - Preferred
Concept UI M0527523
Scope note A histone chaperone protein that plays a role in the deposition of NUCLEOSOMES on newly synthesized DNA. It is comprised of three different subunits of 48, 60, and 150 kDa molecular size. The 48 kDa subunit, RETINOBLASTOMA-BINDING PROTEIN 4, is also a component of several other protein complexes involved in chromatin remodeling.
Preferred term Chromatin Assembly Factor-1
Entry term(s) Assembly Complex-1, Chromatin
Assembly Factor-1, Chromatin
Chromatin Assembly Complex 1
Chromatin Assembly Complex-1
Chromatin Assembly Factor 1
Chromatin Assembly Complex-1, p150 Subunit - Narrower
Concept UI M0527547
Preferred term Chromatin Assembly Complex-1, p150 Subunit
Entry term(s) Chromatin Assembly Complex 1, p150 Subunit
Chromatin Assembly Complex-1, p60 Subunit - Narrower
Concept UI M0527548
Preferred term Chromatin Assembly Complex-1, p60 Subunit
Entry term(s) Chromatin Assembly Complex 1, p60 Subunit



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