Search
Descriptor English: Nuclear Receptor Co-Repressor 2
Descriptor Spanish: Co-Represor 2 de Receptor Nuclear
Descriptor correpresor 2 de receptores nucleares
Scope note: Proteína nuclear correpresora que muestra especificidad por los RECEPTORES DEL ÁCIDO RETINOICO y los RECEPTORES DE HORMONAS TIROIDEAS. La disociación de este correpresor de los receptores nucleares depende generalmente de ligandos pero puede darse también a través de su fosforilación mediante miembros del SISTEMA DE SEÑALIZACIÓN MAP CINASA. La proteína contiene dos dominios de interacción con receptores nucleares y cuatro dominios represores y está estrechamente relacionado estructuralmente con el CORREPRESOR 1 DE RECEPTORES NUCLEARES.
Descriptor Portuguese: Correpressor 2 de Receptor Nuclear
Descriptor French: Corépresseur-2 de récepteur nucléaire
Entry term(s): Co-repressor, SMRT
Co-repressor, TRAC
Nuclear Receptor Co Repressor 2
Receptor-associating Factor, T3
SMRT Co repressor
SMRT Co-repressor
Silencing Mediator of Retinoic Acid and Thyroid Hormone Receptor
T3 Receptor associating Factor
T3 Receptor-associating Factor
TRAC Co repressor
TRAC Co-repressor
Tree number(s): D12.776.930.780.625.400
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D056985
Scope note: A nuclear co-repressor protein that shows specificity for RETINOIC ACID RECEPTORS and THYROID HORMONE RECEPTORS. The dissociation of this co-repressor from nuclear receptors is generally ligand-dependent, but can also occur by way of its phosphorylation by members of the MAP KINASE SIGNALING SYSTEM. The protein contains two nuclear receptor interaction domains and four repressor domains and is closely-related in structure to NUCLEAR RECEPTOR CO-REPRESSOR 1.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2010; NUCLEAR RECEPTOR CO-REPRESSOR 2 was indexed under DNA-BINDING PROTEINS and REPRESSOR PROTEINS 1995-2009
History Note: 2010(1995)
DeCS ID: 53661
Unique ID: D056985
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2010/01/01
Date of Entry: 2009/07/06
Revision Date: 2015/06/29
Nuclear Receptor Co-Repressor 2 - Preferred
Concept UI M0533724
Scope note A nuclear co-repressor protein that shows specificity for RETINOIC ACID RECEPTORS and THYROID HORMONE RECEPTORS. The dissociation of this co-repressor from nuclear receptors is generally ligand-dependent, but can also occur by way of its phosphorylation by members of the MAP KINASE SIGNALING SYSTEM. The protein contains two nuclear receptor interaction domains and four repressor domains and is closely-related in structure to NUCLEAR RECEPTOR CO-REPRESSOR 1.
Preferred term Nuclear Receptor Co-Repressor 2
Entry term(s) Co-repressor, SMRT
Co-repressor, TRAC
Nuclear Receptor Co Repressor 2
Receptor-associating Factor, T3
SMRT Co repressor
SMRT Co-repressor
Silencing Mediator of Retinoic Acid and Thyroid Hormone Receptor
T3 Receptor associating Factor
T3 Receptor-associating Factor
TRAC Co repressor
TRAC Co-repressor



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey