| Descriptor English: | DAX-1 Orphan Nuclear Receptor | ||||||
| Descriptor Spanish: |
Receptor Nuclear Huérfano DAX-1
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| Descriptor Portuguese: | Receptor Nuclear Órfão DAX-1 | ||||||
| Descriptor French: | Récepteur nucléaire orphelin DAX-1 | ||||||
| Entry term(s): |
DAX 1 Orphan Nuclear Receptor DSS AHC Critical Region on the X Chromosome, Gene 1 Protein DSS-AHC Critical Region on the X Chromosome, Gene 1 Protein NR0B1 Protein Nuclear Receptor 0B1 Nuclear Receptor DAX 1 Nuclear Receptor DAX-1 Nuclear Receptor NR0B1 Nuclear Receptor Subfamily 0, Group B, Member 1 |
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| Tree number(s): |
D12.776.826.209.059 D12.776.930.780.625.186 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D057137 | ||||||
| Scope note: | An orphan nuclear receptor that is implicated in regulation of steroidogenic pathways. It is unlike most orphan nuclear receptors in that it appears to lack an essential DNA-binding domain and instead acts as a transcriptional co-repressor. Mutations in the gene Dax-1 cause congenital adrenal hypoplasia. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Public MeSH Note: | 2010; DAX-1 ORPHAN NUCLEAR RECEPTOR was indexed under DNA-BINDING PROTEINS, REPRESSOR PROTEINS, and RECEPTORS, RETINOIC ACID 2003-2009, and under TRANSCRIPTION FACTORS 1994-2003 |
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| History Note: | 2010(1995) |
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| DeCS ID: | 53658 | ||||||
| Unique ID: | D057137 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2010/01/01 | ||||||
| Date of Entry: | 2009/07/06 | ||||||
| Revision Date: | 2016/07/01 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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DAX-1 Orphan Nuclear Receptor
- Preferred
| Concept UI |
M0534812 |
| Scope note | An orphan nuclear receptor that is implicated in regulation of steroidogenic pathways. It is unlike most orphan nuclear receptors in that it appears to lack an essential DNA-binding domain and instead acts as a transcriptional co-repressor. Mutations in the gene Dax-1 cause congenital adrenal hypoplasia. |
| Preferred term | DAX-1 Orphan Nuclear Receptor |
| Entry term(s) |
DAX 1 Orphan Nuclear Receptor DSS AHC Critical Region on the X Chromosome, Gene 1 Protein DSS-AHC Critical Region on the X Chromosome, Gene 1 Protein NR0B1 Protein Nuclear Receptor 0B1 Nuclear Receptor DAX 1 Nuclear Receptor DAX-1 Nuclear Receptor NR0B1 Nuclear Receptor Subfamily 0, Group B, Member 1 |
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