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Descriptor English: Repressor Proteins
Descriptor Spanish: Proteínas Represoras
Descriptor proteínas represoras
Entry term(s) moléculas represoras
Scope note: Proteínas que se unen normalmente al locus operador de un operón, impidiendo así la transcripción de los genes estructurales. En la inducción enzimática, el sustrato de la enzima inducible se une a la proteína represora, lo que hace que esta se separe del operador y libera los genes estructurales para la transcripción. En la represión enzimática, el producto final de la secuencia enzimática se une a la proteína represora libre, el complejo que se produce se une entonces al operador e impide la transcripción de los genes estructurales.
Descriptor Portuguese: Proteínas Repressoras
Descriptor French: Protéines de répression
Entry term(s): Proteins, Repressor
Repressor Molecules
Silencing Factors, Transcriptional
Transcriptional Silencing Factors
Tree number(s): D12.776.260.703
D12.776.930.780
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D012097
Scope note: Proteins which maintain the transcriptional quiescence of specific GENES or OPERONS. Classical repressor proteins are DNA-binding proteins that are normally bound to the OPERATOR REGION of an operon, or the ENHANCER SEQUENCES of a gene until a signal occurs that causes their release.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Bacterial Proteins (1966-1978)
Enzyme Repression (1966-1978)
Genes, Regulator (1968-1978)
Transcription, Genetic (1973-1978)
Public MeSH Note: 91; was see under TRANSCRIPTION FACTORS 1979-90
History Note: 91(79); was see under TRANSCRIPTION FACTORS 1979-90
DeCS ID: 12518
Unique ID: D012097
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1978/05/19
Revision Date: 2015/06/29
Repressor Proteins - Preferred
Concept UI M0018809
Scope note Proteins which maintain the transcriptional quiescence of specific GENES or OPERONS. Classical repressor proteins are DNA-binding proteins that are normally bound to the OPERATOR REGION of an operon, or the ENHANCER SEQUENCES of a gene until a signal occurs that causes their release.
Preferred term Repressor Proteins
Entry term(s) Proteins, Repressor
Transcriptional Silencing Factors - Narrower
Concept UI M0533641
Preferred term Transcriptional Silencing Factors
Entry term(s) Silencing Factors, Transcriptional
Repressor Molecules - Broader
Concept UI M0018810
Preferred term Repressor Molecules



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