| Descriptor English: | Histone Deacetylase Inhibitors | ||||||
| Descriptor Spanish: | Inhibidores de Histona Desacetilasas 
 | ||||||
| Descriptor Portuguese: | Inibidores de Histona Desacetilases | ||||||
| Descriptor French: | Inhibiteurs de désacétylase d'histone | ||||||
| Entry term(s): | Deacetylase Inhibitor, Histone Deacetylase Inhibitors, Histone HDAC Inhibitor HDAC Inhibitors Histone Deacetylase Inhibitor Inhibitor, HDAC Inhibitor, Histone Deacetylase Inhibitors, HDAC Inhibitors, Histone Deacetylase | ||||||
| Tree number(s): | D27.505.519.389.360 | ||||||
| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D056572 | ||||||
| Scope note: | Compounds that inhibit HISTONE DEACETYLASES. This class of drugs may influence gene expression by increasing the level of acetylated HISTONES in specific CHROMATIN domains. | ||||||
| Allowable Qualifiers: | AD                                                            administration & dosage AE adverse effects AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine | ||||||
| Previous Indexing: | Histone Deacetylases/antagonists & inhibitors (1978-2009) | ||||||
| Public MeSH Note: | 2010 | ||||||
| History Note: | 2010 | ||||||
| DeCS ID: | 53667 | ||||||
| Unique ID: | D056572 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2010/01/01 | ||||||
| Date of Entry: | 2009/07/06 | ||||||
| Revision Date: | 2020/05/27 | 
- 
                                    - 
                                        CHEMICALS AND DRUGS
 
 Chemical Actions and Uses [D27]Chemical Actions and Uses
|  | 
                        
                                                                    
                        Histone Deacetylase Inhibitors                                            
                                        - Preferred                                        
                                                                
                                
                        
                        
                        
                        
                        
                    
                    
                
                | Concept UI | M0527853 | 
| Scope note | Compounds that inhibit HISTONE DEACETYLASES. This class of drugs may influence gene expression by increasing the level of acetylated HISTONES in specific CHROMATIN domains. | 
| Preferred term | Histone Deacetylase Inhibitors | 
| Entry term(s) | Deacetylase Inhibitor, Histone Deacetylase Inhibitors, Histone HDAC Inhibitor HDAC Inhibitors Histone Deacetylase Inhibitor Inhibitor, HDAC Inhibitor, Histone Deacetylase Inhibitors, HDAC Inhibitors, Histone Deacetylase | 
We want your feedback on the new DeCS / MeSH website
We invite you to complete a survey that will take no more than 3 minutes.
Go to survey