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Descriptor English: Septins
Descriptor Spanish: Septinas
Descriptor septinas
Entry term(s) septina
Scope note: Familia de proteínas que se unen a GTP identificadas inicialmente en LEVADURAS en las que, según se demostró, inician el proceso de septación y de formación de yemas. Las septinas forman complejos heterooligoméricos que están compuestos de subunidades septínicas distintas. Estos complejos pueden actuar como elementos citoesqueléticos que desempeñan papeles importantes en la CITOCINESIA, reorganización citoesquelética,TRANSPORTE BIOLÓGICO y dinámica de membranas.
Descriptor Portuguese: Septinas
Descriptor French: Septines
Entry term(s): Septin
Tree number(s): D08.811.277.040.330.300.700
D12.776.157.325.757
D12.776.220.932
D12.776.476.338.700
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D058112
Scope note: A family of GTP-binding proteins that were initially identified in YEASTS where they were shown to initiate the process of septation and bud formation. Septins form into hetero-oligomeric complexes that are comprised of several distinct septin subunits. These complexes can act as cytoskeletal elements that play important roles in CYTOKINESIS, cytoskeletal reorganization, BIOLOGICAL TRANSPORT, and membrane dynamics.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.6.1.-
Public MeSH Note: 2011
History Note: 2011
DeCS ID: 54040
Unique ID: D058112
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2011/01/01
Date of Entry: 2010/06/25
Revision Date: 2020/05/27
Septins - Preferred
Concept UI M0540892
Scope note A family of GTP-binding proteins that were initially identified in YEASTS where they were shown to initiate the process of septation and bud formation. Septins form into hetero-oligomeric complexes that are comprised of several distinct septin subunits. These complexes can act as cytoskeletal elements that play important roles in CYTOKINESIS, cytoskeletal reorganization, BIOLOGICAL TRANSPORT, and membrane dynamics.
Preferred term Septins
Entry term(s) Septin



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