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Descriptor English: Class I Phosphatidylinositol 3-Kinases
Descriptor Spanish: Fosfatidilinositol 3-Quinasa Clase I
Descriptor fosfatidilinositol 3-cinasas de clase I
Entry term(s) fosfatidilinositol 3-cinasa clase I
Scope note: Subclase de fosfatidilinositol 3-cinasa que incluye enzimas con especificidad por el 1-fosfatidilinositol, 1-fosfatidilinositol 4-fosfato, y 1-fosfatidilinositol 4,5 bisfosfato. Los miembros de esta subclase enzimática son activados por los recptores de la superficie celular y se dan como heterodímeros de subunidades enzimáticas y reguladoras.
Descriptor Portuguese: Classe I de Fosfatidilinositol 3-Quinases
Descriptor French: Phosphatidylinositol 3-kinases de classe I
Entry term(s): Class I Phosphatidylinositol 3 Kinase
Class I Phosphatidylinositol 3 Kinases
Class I Phosphatidylinositol 3-Kinase
Phosphatidylinositol 3 Kinase, Class I
Phosphatidylinositol 3-Kinase, Class I
Tree number(s): D08.811.913.696.620.500.100.100
D08.811.913.696.620.500.200.100
D12.776.476.556.100.100
D12.776.476.556.200.100
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D058534
Scope note: A phosphatidylinositol 3-kinase subclass that includes enzymes with a specificity for 1-phosphatidylinositol, 1-phosphatidylinositol 4-phosphate, and 1-phosphatidylinositol 4,5-bisphosphate. Members of this enzyme subclass are activated by cell surface receptors and occur as heterodimers of enzymatic and regulatory subunits.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.7.1.137
Previous Indexing: Phosphatidylinositol 3-Kinases (1998-2010)
Public MeSH Note: 2011
History Note: 2011
DeCS ID: 54044
Unique ID: D058534
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2011/01/01
Date of Entry: 2010/06/25
Class I Phosphatidylinositol 3-Kinases - Preferred
Concept UI M0543055
Scope note A phosphatidylinositol 3-kinase subclass that includes enzymes with a specificity for 1-phosphatidylinositol, 1-phosphatidylinositol 4-phosphate, and 1-phosphatidylinositol 4,5-bisphosphate. Members of this enzyme subclass are activated by cell surface receptors and occur as heterodimers of enzymatic and regulatory subunits.
Preferred term Class I Phosphatidylinositol 3-Kinases
Entry term(s) Class I Phosphatidylinositol 3 Kinase
Class I Phosphatidylinositol 3 Kinases
Class I Phosphatidylinositol 3-Kinase
Phosphatidylinositol 3 Kinase, Class I
Phosphatidylinositol 3-Kinase, Class I



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