| Descriptor English: | Class Ib Phosphatidylinositol 3-Kinase | ||||||
| Descriptor Spanish: |
Fosfatidilinositol 3-Quinasa Clase Ib
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| Descriptor Portuguese: | Classe Ib de Fosfatidilinositol 3-Quinase | ||||||
| Descriptor French: | Phosphatidylinositol 3-kinases de classe Ib | ||||||
| Entry term(s): |
Class Ib Phosphatidylinositol 3 Kinase Class Ib Phosphatidylinositol 3 Kinase, p101 Subunit Class Ib Phosphatidylinositol 3 Kinase, p110gamma Subunit Class Ib Phosphatidylinositol 3 Kinase, p84 Subunit Class Ib Phosphatidylinositol 3 Kinase, p87 Subunit Class Ib Phosphatidylinositol 3 Kinases Class Ib Phosphatidylinositol 3-Kinase, p101 Subunit Class Ib Phosphatidylinositol 3-Kinase, p110gamma Subunit Class Ib Phosphatidylinositol 3-Kinase, p84 Subunit Class Ib Phosphatidylinositol 3-Kinase, p87 Subunit Class Ib Phosphatidylinositol 3-Kinases Phosphatidylinositol 3 Kinase, Class Ib Phosphatidylinositol 3-Kinase, Class Ib Phosphoinositide 3 Kinase, Regulatory Subunit 5 Phosphoinositide-3-Kinase p101 Subunit Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide Phosphoinositide-3-Kinase, Regulatory Subunit 5 Subunit, Phosphoinositide-3-Kinase p101 p101 Subunit, Phosphoinositide 3 Kinase p101 Subunit, Phosphoinositide-3-Kinase p110gamma Subunit, Class Ib Phosphatidylinositol 3 Kinase p110gamma Subunit, Class Ib Phosphatidylinositol 3-Kinase p84 Subunit, Class Ib Phosphatidylinositol 3 Kinase p84 Subunit, Class Ib Phosphatidylinositol 3-Kinase p87 Subunit, Class Ib Phosphatidylinositol 3 Kinase p87 Subunit, Class Ib Phosphatidylinositol 3-Kinase |
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| Tree number(s): |
D08.811.913.696.620.500.100.100.200 D08.811.913.696.620.500.200.100.200 D12.776.476.556.100.100.200 D12.776.476.556.200.100.200 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D058544 | ||||||
| Scope note: | A phosphatidylinositol 3-kinase subclass that includes enzymes formed through the association of a p110gamma catalytic subunit and one of the three regulatory subunits of 84, 87, and 101 kDa in size. This subclass of enzymes is a downstream target of G PROTEIN-COUPLED RECEPTORS. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 2.7.1.137 | ||||||
| Previous Indexing: |
Phosphatidylinositol 3-Kinases (1998-2010) |
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| Public MeSH Note: | 2011 |
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| History Note: | 2011 |
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| DeCS ID: | 54046 | ||||||
| Unique ID: | D058544 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2011/01/01 | ||||||
| Date of Entry: | 2010/06/25 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Class Ib Phosphatidylinositol 3-Kinase
- Preferred
Class Ib Phosphatidylinositol 3-Kinase, p110gamma Subunit
- Narrower
Class Ib Phosphatidylinositol 3-Kinase, p87 Subunit
- Narrower
Class Ib Phosphatidylinositol 3-Kinase, p101 Subunit
- Narrower
Class Ib Phosphatidylinositol 3-Kinase, p84 Subunit
- Narrower
| Concept UI |
M0543149 |
| Scope note | A phosphatidylinositol 3-kinase subclass that includes enzymes formed through the association of a p110gamma catalytic subunit and one of the three regulatory subunits of 84, 87, and 101 kDa in size. This subclass of enzymes is a downstream target of G PROTEIN-COUPLED RECEPTORS. |
| Preferred term | Class Ib Phosphatidylinositol 3-Kinase |
| Entry term(s) |
Class Ib Phosphatidylinositol 3 Kinase Class Ib Phosphatidylinositol 3 Kinases Class Ib Phosphatidylinositol 3-Kinases Phosphatidylinositol 3 Kinase, Class Ib Phosphatidylinositol 3-Kinase, Class Ib |
| Concept UI |
M0543163 |
| Preferred term | Class Ib Phosphatidylinositol 3-Kinase, p110gamma Subunit |
| Entry term(s) |
Class Ib Phosphatidylinositol 3 Kinase, p110gamma Subunit Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide p110gamma Subunit, Class Ib Phosphatidylinositol 3 Kinase p110gamma Subunit, Class Ib Phosphatidylinositol 3-Kinase |
| Concept UI |
M0543181 |
| Preferred term | Class Ib Phosphatidylinositol 3-Kinase, p87 Subunit |
| Entry term(s) |
Class Ib Phosphatidylinositol 3 Kinase, p87 Subunit p87 Subunit, Class Ib Phosphatidylinositol 3 Kinase p87 Subunit, Class Ib Phosphatidylinositol 3-Kinase |
| Concept UI |
M0543166 |
| Preferred term | Class Ib Phosphatidylinositol 3-Kinase, p101 Subunit |
| Entry term(s) |
Class Ib Phosphatidylinositol 3 Kinase, p101 Subunit Phosphoinositide 3 Kinase, Regulatory Subunit 5 Phosphoinositide-3-Kinase p101 Subunit Phosphoinositide-3-Kinase, Regulatory Subunit 5 Subunit, Phosphoinositide-3-Kinase p101 p101 Subunit, Phosphoinositide 3 Kinase p101 Subunit, Phosphoinositide-3-Kinase |
| Concept UI |
M0543182 |
| Preferred term | Class Ib Phosphatidylinositol 3-Kinase, p84 Subunit |
| Entry term(s) |
Class Ib Phosphatidylinositol 3 Kinase, p84 Subunit p84 Subunit, Class Ib Phosphatidylinositol 3 Kinase p84 Subunit, Class Ib Phosphatidylinositol 3-Kinase |
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