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Descriptor in English: Islet Amyloid Polypeptide
Descriptor in Spanish: Polipéptido Amiloide de los Islotes Pancreáticos
Descriptor in Portuguese: Polipeptídeo Amiloide das Ilhotas Pancreáticas
Descriptor in French: Polypeptide amyloïde des ilots
Entry term(s): Amlintide
Amylin
Amylin, Pancreatic
Amyloid Polypeptide, Insulinoma
Amyloid Polypeptide, Islet
IAPP Precursor
IAPP Protein
Insulinoma Amyloid Polypeptide
Insulinoma Amyloid Polypeptide Precursor
Islet Amyloid Polypeptide Precursor
Pancreatic Amylin
Polypeptide, Insulinoma Amyloid
Polypeptide, Islet Amyloid
Tree number(s): D06.472.699.587.334
D12.644.548.586.234
D12.776.049.407.500
Scope note: A pancreatic beta-cell hormone that is co-secreted with INSULIN. It displays an anorectic effect on nutrient metabolism by inhibiting gastric acid secretion, gastric emptying and postprandial GLUCAGON secretion. Islet amyloid polypeptide can fold into AMYLOID FIBRILS that have been found as a major constituent of pancreatic AMYLOID DEPOSITS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
History Note: 2011
DeCS UI: 54057
Descriptor UI: D058228
Date Established: 2011/01/01
Date of Entry: 2010/06/25
Islet Amyloid Polypeptide - Preferred
Concept UI M0541516
Scope note A pancreatic beta-cell hormone that is co-secreted with INSULIN. It displays an anorectic effect on nutrient metabolism by inhibiting gastric acid secretion, gastric emptying and postprandial GLUCAGON secretion. Islet amyloid polypeptide can fold into AMYLOID FIBRILS that have been found as a major constituent of pancreatic AMYLOID DEPOSITS.
Preferred term Islet Amyloid Polypeptide
Entry term(s) Amlintide
Amylin
Amylin, Pancreatic
Amyloid Polypeptide, Insulinoma
Amyloid Polypeptide, Islet
IAPP Protein
Insulinoma Amyloid Polypeptide
Pancreatic Amylin
Polypeptide, Insulinoma Amyloid
Polypeptide, Islet Amyloid
Islet Amyloid Polypeptide Precursor - Narrower
Concept UI M0164943
Preferred term Islet Amyloid Polypeptide Precursor
Entry term(s) IAPP Precursor
Insulinoma Amyloid Polypeptide Precursor



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