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Descriptor English: Decorin
Descriptor Spanish: Decorina
Descriptor decorina
Scope note: Pequeño proteoglicano rico en leucina que interactúa con los COLÁGENOS FIBRILARES y modifica la estructura de la MATRIZ EXTRACELULAR del TEJIDO CONJUNTIVO. Se ha demostrado también que la decorina desempeña otros papeles en la regulación de las respuestas celulares a los FACTORES DE CRECIMIENTO. La proteína contiene una única cadena de glicosaminoglicano y tiene una estructura similar al BIGLICANO.
Descriptor Portuguese: Decorina
Descriptor French: Décorine
Entry term(s): Bone Proteoglycan II
DSPG-II
Proteoglycan II, Bone
Tree number(s): D09.400.430.930.750.625
D09.400.430.930.875.500
D09.698.735.700.750
D12.776.395.650.750.625
D12.776.395.650.875.500
D12.776.860.300.806.750
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D058575
Scope note: A small leucine-rich proteoglycan that interacts with FIBRILLAR COLLAGENS and modifies the EXTRACELLULAR MATRIX structure of CONNECTIVE TISSUE. Decorin has also been shown to play additional roles in the regulation of cellular responses to GROWTH FACTORS. The protein contains a single glycosaminoglycan chain and is similar in structure to BIGLYCAN.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2011; DECORIN was indexed under PROTEOGLYCANS and EXTRACELLULAR MATRIX PROTEINS 1988-2010
History Note: 2011
DeCS ID: 54090
Unique ID: D058575
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2011/01/01
Date of Entry: 2010/06/25
Revision Date: 2016/07/05
Decorin - Preferred
Concept UI M0543326
Scope note A small leucine-rich proteoglycan that interacts with FIBRILLAR COLLAGENS and modifies the EXTRACELLULAR MATRIX structure of CONNECTIVE TISSUE. Decorin has also been shown to play additional roles in the regulation of cellular responses to GROWTH FACTORS. The protein contains a single glycosaminoglycan chain and is similar in structure to BIGLYCAN.
Preferred term Decorin
Entry term(s) Bone Proteoglycan II
DSPG-II
Proteoglycan II, Bone



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