| Descriptor English: | Small Leucine-Rich Proteoglycans | ||||||
| Descriptor Spanish: |
Proteoglicanos Pequeños Ricos en Leucina
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| Descriptor Portuguese: | Proteoglicanos Pequenos Ricos em Leucina | ||||||
| Descriptor French: | Petits protéoglycanes riches en leucine | ||||||
| Entry term(s): |
Leucine-Rich Proteoglycan, Small Proteoglycan, SLRP Proteoglycan, Small Leucine-Rich SLRP Proteoglycan SLRP Proteoglycans Small Leucine Rich Proteoglycan Small Leucine Rich Proteoglycans Small Leucine Rich Repeat Proteoglycan Small Leucine Rich Repeat Proteoglycans Small Leucine-Rich Proteoglycan Small Leucine-Rich Repeat Proteoglycan Small Leucine-Rich Repeat Proteoglycans |
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| Tree number(s): |
D09.400.430.930.875 D09.698.735.700 D12.776.395.650.875 D12.776.860.300.806 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000071232 | ||||||
| Scope note: | A proteoglycan family (SLRPs) that is defined by a central domain which consists of a variable number of repeats of the motif LXXLxLXXNxL, where L may be LEUCINE; ISOLEUCINE; VALINE; or other hydrophobic amino acids. The N-terminal contains four conserved CYSTEINE residues and may be modified depending on function. SLRPs provide structural support to the EXTRACELLULAR MATRIX and are critical for regulating its assembly and dynamics at CELL-MATRIX JUNCTIONS. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Previous Indexing: |
Proteoglycans (1996-2016) |
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| Public MeSH Note: | 2017 |
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| History Note: | 2017 |
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| DeCS ID: | 56522 | ||||||
| Unique ID: | D000071232 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2017/01/01 | ||||||
| Date of Entry: | 2016/07/08 | ||||||
| Revision Date: | 2020/05/27 |
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CHEMICALS AND DRUGS
Carbohydrates [D09]Carbohydrates -
CHEMICALS AND DRUGS
Carbohydrates [D09]Carbohydrates -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Small Leucine-Rich Proteoglycans
- Preferred
| Concept UI |
M000613763 |
| Scope note | A proteoglycan family (SLRPs) that is defined by a central domain which consists of a variable number of repeats of the motif LXXLxLXXNxL, where L may be LEUCINE; ISOLEUCINE; VALINE; or other hydrophobic amino acids. The N-terminal contains four conserved CYSTEINE residues and may be modified depending on function. SLRPs provide structural support to the EXTRACELLULAR MATRIX and are critical for regulating its assembly and dynamics at CELL-MATRIX JUNCTIONS. |
| Preferred term | Small Leucine-Rich Proteoglycans |
| Entry term(s) |
Leucine-Rich Proteoglycan, Small Proteoglycan, SLRP Proteoglycan, Small Leucine-Rich SLRP Proteoglycan SLRP Proteoglycans Small Leucine Rich Proteoglycan Small Leucine Rich Proteoglycans Small Leucine Rich Repeat Proteoglycan Small Leucine Rich Repeat Proteoglycans Small Leucine-Rich Proteoglycan Small Leucine-Rich Repeat Proteoglycan Small Leucine-Rich Repeat Proteoglycans |
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