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Descriptor English: Telomere Shortening
Descriptor Spanish: Acortamiento del Telómero
Descriptor acortamiento telomérico
Entry term(s) acortamiento del telómero
Scope note: La pérdida de alguna secuencia de TELÓMERO durante la REPLICACIÓN DEL ADN del primero de los varios pares de bases de una molécula de ADN LINEAR; o del DAÑO DEL ADN. Las células tienen varios mecanismos para restablecer la longitud (HOMEOSTASIS DEL TELÓMERO). El acortamiento del telómero participa en la progresión del ENVEJECIMIENTO CELULAR.
Descriptor Portuguese: Encurtamento do Telômero
Descriptor French: Raccourcissement des télomères
Entry term(s): Shortening, Telomere
Shortenings, Telomere
Telomere Shortenings
Tree number(s): G02.111.225.940
G04.043.630
G05.226.940
G07.345.124.130.630
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D059506
Scope note: The loss of some TELOMERE sequence during DNA REPLICATION of the first several base pairs of a linear DNA molecule; or from DNA DAMAGE. Cells have various mechanisms to restore length (TELOMERE HOMEOSTASIS.) Telomere shortening is involved in the progression of CELL AGING.
Allowable Qualifiers: DE drug effects
GE genetics
IM immunology
PH physiology
RE radiation effects
Previous Indexing: Telomere (1992-2011)
Public MeSH Note: 2012
History Note: 2012
Related: Telomere Homeostasis MeSH
DeCS ID: 54773
Unique ID: D059506
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2012/01/01
Date of Entry: 2011/06/24
Revision Date: 2016/06/17
Telomere Shortening - Preferred
Concept UI M0550398
Scope note The loss of some TELOMERE sequence during DNA REPLICATION of the first several base pairs of a linear DNA molecule; or from DNA DAMAGE. Cells have various mechanisms to restore length (TELOMERE HOMEOSTASIS.) Telomere shortening is involved in the progression of CELL AGING.
Preferred term Telomere Shortening
Entry term(s) Shortening, Telomere
Shortenings, Telomere
Telomere Shortenings



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