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Descriptor English: DNA Damage Tolerance
Descriptor Spanish: Tolerancia al Daño del ADN
Descriptor tolerancia al daño del ADN
Entry term(s) intercambio de molde posreplicativo
intercambio de molde replicativo
reparación posreplicación
reparación posreplicativa
reparación posterior a la replicación
reparación postreplicación
reparación postreplicativa
replicación tolerante con el daño del ADN
reversión de la horquilla de replicación
vías de evitación del daño del ADN
vías de tolerancia del daño del ADN
Scope note: Estrategias que utilizan las células para continuar la replicación del ADN cuando las ADN-polimerasas replicativas se detienen en las horquillas de replicación bloqueadas por daños del ADN. Estos mecanismos de replicación tolerante al daño del ADN permiten seguir adelante evitando la zona de DAÑO DEL ADN, el cual puede repararse posteriormente mediante diversos mecanismos de REPARACIÓN del ADN.
Descriptor Portuguese: Tolerância ao Dano no DNA
Descriptor French: Without translation
Entry term(s): DNA Damage Bypass Pathways
DNA Damage Tolerance Pathways
DNA Damage Tolerant Replication
Fork Reversal, Replication
Post Replication Repair
Post-Replication Repair
Post-Replication Repairs
Postreplication Repair
Postreplicative Repair
Postreplicative Template Switching
Replication Fork Reversal
Replication Template Switching
Template Switching, Postreplicative
Template Switching, Replication
Tree number(s): G02.111.225.380
G05.226.380
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000097122
Scope note: Strategies that cells use to continue DNA replication when replicative DNA polymerases stall at DNA damage-blocked replication forks. These DNA damage tolerant replication mechanisms bypass the DNA DAMAGE, which may be repaired subsequently by various DNA REPAIR mechanisms.
Allowable Qualifiers: DE drug effects
GE genetics
IM immunology
PH physiology
RE radiation effects
Public MeSH Note: 2024
History Note: 2024
Related: DNA Repair MeSH
DeCS ID: 60555
Unique ID: D000097122
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2024/01/01
Date of Entry: 2023/07/26
Revision Date: 2023/05/26
DNA Damage Tolerance - Preferred
Concept UI M000763247
Scope note Strategies that cells use to continue DNA replication when replicative DNA polymerases stall at DNA damage-blocked replication forks. These DNA damage tolerant replication mechanisms bypass the DNA DAMAGE, which may be repaired subsequently by various DNA REPAIR mechanisms.
Preferred term DNA Damage Tolerance
Entry term(s) DNA Damage Bypass Pathways
DNA Damage Tolerance Pathways
DNA Damage Tolerant Replication
Post Replication Repair
Post-Replication Repair
Post-Replication Repairs
Postreplication Repair
Postreplicative Repair
Replication Fork Reversal - Narrower
Concept UI M000763347
Preferred term Replication Fork Reversal
Entry term(s) Fork Reversal, Replication
Postreplicative Template Switching - Narrower
Concept UI M000763279
Preferred term Postreplicative Template Switching
Entry term(s) Replication Template Switching
Template Switching, Postreplicative
Template Switching, Replication



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