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Descriptor English: Peripheral Tolerance
Descriptor Spanish: Tolerancia Periférica
Descriptor tolerancia periférica
Scope note: El mecanismo en los órganos linfoides periféricos (GANGLIOS LINFÁTICOS, BAZO, AMÍGDALAS y tejido linfoide asociado a las mucosas) que previene que los linfocitos maduros reaccionen con los AUTOANTÍGENOS. Se logra por diversos medios, entre ellos ANERGIA CLONAL y SUPRESIÓN CLONAL.
Descriptor Portuguese: Tolerância Periférica
Descriptor French: Tolérance périphérique
Entry term(s): Tolerance, Peripheral
Tree number(s): G12.535.425.800.600
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D061166
Scope note: The mechanism, in peripheral lymphoid organs (LYMPH NODES; SPLEEN; TONSILS; and mucosal-associated lymphoid tissue), that prevents mature lymphocytes from reacting to SELF-ANTIGENS. This is accomplished through a variety of means including CLONAL ANERGY and CLONAL DELETION.
Allowable Qualifiers: DE drug effects
GE genetics
IM immunology
PH physiology
RE radiation effects
Previous Indexing: Immune Tolerance (1989-2011)
Public MeSH Note: 2012
History Note: 2012
DeCS ID: 54819
Unique ID: D061166
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2012/01/01
Date of Entry: 2011/06/24
Revision Date: 2016/06/23
Peripheral Tolerance - Preferred
Concept UI M0556536
Scope note The mechanism, in peripheral lymphoid organs (LYMPH NODES; SPLEEN; TONSILS; and mucosal-associated lymphoid tissue), that prevents mature lymphocytes from reacting to SELF-ANTIGENS. This is accomplished through a variety of means including CLONAL ANERGY and CLONAL DELETION.
Preferred term Peripheral Tolerance
Entry term(s) Tolerance, Peripheral



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