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Descriptor English: Voltage-Gated Sodium Channel beta-3 Subunit
Descriptor Spanish: Subunidad beta-3 de Canal de Sodio Activado por Voltaje
Descriptor subunidades beta-3 de los canales del sodio dependientes de voltaje
Scope note: Subtipo de la subunidad beta de los canales del sodio dependientes de voltaje, que no se une covalentemente con las subunidades alfa dependientes de voltaje. Defectos en el gen SCN3B, que codifica esta subunidad beta, están asociados con el síndrome de Brugada 7.
Descriptor Portuguese: Subunidade beta-3 do Canal de Sódio Disparado por Voltagem
Descriptor French: Sous-unité bêta-3 des canaux sodiques voltage-dépendants
Entry term(s): SCN3B Sodium Channel beta Subunit
Voltage Gated Sodium Channel beta 3 Subunit
Tree number(s): D12.776.157.530.400.875.750.960.300
D12.776.543.550.450.875.750.970.300
D12.776.543.585.400.875.750.970.300
D12.776.631.960.970.300
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D062549
Scope note: A voltage-gated sodium channel beta subunit subtype that non-covalently associates with voltage-gated alpha subunits. Defects in the SCN3B gene which codes for this beta subunit are associated with Brugada syndrome 7.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Entry Combination: antagonists & inhibitors:Voltage-Gated Sodium Channel Blockers
agonists:Voltage-Gated Sodium Channel Agonists
Previous Indexing: Sodium Channels (1989-2012)
Public MeSH Note: 2013
History Note: 2013
Related: Brugada Syndrome MeSH
DeCS ID: 54959
Unique ID: D062549
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2013/01/01
Date of Entry: 2012/07/03
Revision Date: 2016/07/01
Voltage-Gated Sodium Channel beta-3 Subunit - Preferred
Concept UI M0568572
Scope note A voltage-gated sodium channel beta subunit subtype that non-covalently associates with voltage-gated alpha subunits. Defects in the SCN3B gene which codes for this beta subunit are associated with Brugada syndrome 7.
Preferred term Voltage-Gated Sodium Channel beta-3 Subunit
Entry term(s) SCN3B Sodium Channel beta Subunit
Voltage Gated Sodium Channel beta 3 Subunit



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