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Descriptor English: Voltage-Gated Sodium Channel beta-4 Subunit
Descriptor Spanish: Subunidad beta-4 de Canal de Sodio Activado por Voltaje
Descriptor subunidades beta-4 de los canales del sodio dependientes de voltaje
Scope note: Subtipo de la subunidad beta de los canales del sodio dependientes de voltaje, que se une covalentemente con las subunidades alfa dependientes de voltaje. Defectos en el gen SCN4B, que codifica esta subunidad beta, están asociados con el síndrome QT largo 10.
Descriptor Portuguese: Subunidade beta-4 do Canal de Sódio Disparado por Voltagem
Descriptor French: Sous-unité bêta-4 des canaux sodiques voltage-dépendants
Entry term(s): SCN4B Sodium Channel beta Subunit
Voltage Gated Sodium Channel beta 4 Subunit
Tree number(s): D12.776.157.530.400.875.750.960.650
D12.776.543.550.450.875.750.970.400
D12.776.543.585.400.875.750.970.650
D12.776.631.960.970.650
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D062585
Scope note: A voltage-gated sodium channel beta subunit subtype that covalently associates with voltage-gated alpha subunits. Defects in the SCN4B gene, which codes for this beta subunit, are associated with long QT syndrome-10.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Entry Combination: antagonists & inhibitors:Voltage-Gated Sodium Channel Blockers
agonists:Voltage-Gated Sodium Channel Agonists
Previous Indexing: Sodium Channels (1988-2012)
Public MeSH Note: 2013
History Note: 2013
Related: Long QT Syndrome MeSH
DeCS ID: 54960
Unique ID: D062585
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2013/01/01
Date of Entry: 2012/07/03
Revision Date: 2016/07/01
Voltage-Gated Sodium Channel beta-4 Subunit - Preferred
Concept UI M0568718
Scope note A voltage-gated sodium channel beta subunit subtype that covalently associates with voltage-gated alpha subunits. Defects in the SCN4B gene, which codes for this beta subunit, are associated with long QT syndrome-10.
Preferred term Voltage-Gated Sodium Channel beta-4 Subunit
Entry term(s) SCN4B Sodium Channel beta Subunit
Voltage Gated Sodium Channel beta 4 Subunit



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