Search
Descriptor English: Sialic Acid Binding Ig-like Lectin 3
Descriptor Spanish: Lectina 3 Similar a Ig de Unión al Ácido Siálico
Descriptor lectina 3 similar a Ig de unión al ácido siálico
Scope note: Lectina de unión al ácido siálico de 67kDa, específica de CÉLULAS MIELOIDES y CÉLULAS PRECURSORAS DE MONOCITOS Y MACRÓFAGOS. Esta proteína es el subtipo de menor tamaño de todas las SIGLEC y contiene un único dominio C2-set. Interviene en la señalización intracelular vía su interacción con la PROTEÍNA TIROSINA FOSFATASA SHP-1 y la PROTEÍNA TIROSINA FOSFATASA SHP-2.
Descriptor Portuguese: Lectina 3 Semelhante a Ig de Ligação ao Ácido Siálico
Descriptor French: Lectine-3 de type Ig liant l'acide sialique
Entry term(s): Antigen, CD33
Antigens, CD33
CD33 Antigen
CD33 Antigens
Glycoprotein gp67
Sialic Acid Binding Ig like Lectin 3
Siglec-3
gp67, Glycoprotein
Tree number(s): D12.776.503.921.400
D23.050.301.264.900.565
D23.101.100.900.565
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D063268
Scope note: A 67-kDa sialic acid binding lectin that is specific for MYELOID CELLS and MONOCYTE-MACROPHAGE PRECURSOR CELLS. This protein is the smallest siglec subtype and contains a single immunoglobulin C2-set domain. It may play a role in intracellular signaling via its interaction with SHP-1 PROTEIN-TYROSINE PHOSPHATASE and SHP-2 PROTEIN-TYROSINE PHOSPHATASE.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2013; CD33 ANTIGEN (now SIALIC ACID BINDING IG-LIKE LECTIN 3) was indexed under ANTINGENS, DIFFERENTIATION, MYELOMONOCYTIC and ANTIGENS, CD 2003-2012, and under NEOPLASM ANTIGENS 1988-2002
History Note: 2013
Related: Immunoglobulin Domains MeSH
DeCS ID: 54971
Unique ID: D063268
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2013/01/01
Date of Entry: 2012/07/03
Revision Date: 2017/05/24
Sialic Acid Binding Ig-like Lectin 3 - Preferred
Concept UI M0572476
Scope note A 67-kDa sialic acid binding lectin that is specific for MYELOID CELLS and MONOCYTE-MACROPHAGE PRECURSOR CELLS. This protein is the smallest siglec subtype and contains a single immunoglobulin C2-set domain. It may play a role in intracellular signaling via its interaction with SHP-1 PROTEIN-TYROSINE PHOSPHATASE and SHP-2 PROTEIN-TYROSINE PHOSPHATASE.
Preferred term Sialic Acid Binding Ig-like Lectin 3
Entry term(s) Antigen, CD33
Antigens, CD33
CD33 Antigen
CD33 Antigens
Glycoprotein gp67
Sialic Acid Binding Ig like Lectin 3
Siglec-3
gp67, Glycoprotein



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey