| Descriptor English: | Platelet Endothelial Cell Adhesion Molecule-1 | ||||||
| Descriptor Spanish: |
Molécula-1 de Adhesión Celular Endotelial de Plaqueta
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| Descriptor Portuguese: | Molécula-1 de Adesão Celular Endotelial a Plaquetas | ||||||
| Descriptor French: | Antigènes CD31 | ||||||
| Entry term(s): |
Antigen, CD31 Antigens, CD31 CD31 Antigen CD31 Antigens PECAM-1 Platelet Endothelial Cell Adhesion Molecule 1 |
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| Tree number(s): |
D09.400.430.890.200.131 D12.776.395.550.200.131 D12.776.543.550.200.131 D23.050.301.264.900.131 D23.050.301.350.131 D23.101.100.900.131 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D019408 | ||||||
| Scope note: | A cell adhesion molecule, composed of a series of Ig-like domains, and expressed on virtually all MONOCYTES; PLATELETS; and GRANULOCYTES. PECAM-1 is highly expressed on endothelial cells and concentrated at the junctions between them. It is essential for TRANSENDOTHELIAL MIGRATION of leukocytes and removal of apoptotic cells by PHAGOCYTES. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Previous Indexing: |
Antigens, Differentiation, Myelomonocytic (1990-1996) Cell Adhesion Molecules (1995-1996) Membrane Glycoproteins (1990-1994) |
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| Public MeSH Note: | 2018; see ANTIGENS, CD31 1997-2017 and CD31 ANTIGEN 1990-1996; PLATELET ENDOTHELIAL CELL ADHESION MOLECULE-1 was indexed under CELL ADHESION MOLECULES 1995-96; under ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC 1990-96; and under MEMBRANE GLYCOPROTEINS 1990-94 |
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| History Note: | 2018 (1990) |
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| Related: |
Immunoglobulin Domains
MeSH | ||||||
| DeCS ID: | 33056 | ||||||
| Unique ID: | D019408 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1997/01/01 | ||||||
| Date of Entry: | 1996/06/10 | ||||||
| Revision Date: | 2017/05/24 |
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CHEMICALS AND DRUGS
Carbohydrates [D09]Carbohydrates -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors
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Platelet Endothelial Cell Adhesion Molecule-1
- Preferred
| Concept UI |
M0028878 |
| Scope note | A cell adhesion molecule, composed of a series of Ig-like domains, and expressed on virtually all MONOCYTES; PLATELETS; and GRANULOCYTES. PECAM-1 is highly expressed on endothelial cells and concentrated at the junctions between them. It is essential for TRANSENDOTHELIAL MIGRATION of leukocytes and removal of apoptotic cells by PHAGOCYTES. |
| Preferred term | Platelet Endothelial Cell Adhesion Molecule-1 |
| Entry term(s) |
Antigen, CD31 Antigens, CD31 CD31 Antigen CD31 Antigens PECAM-1 Platelet Endothelial Cell Adhesion Molecule 1 |
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