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Descriptor English: CD68 Molecule
Descriptor Spanish: Molécula CD68
Descriptor molécula CD68
Entry term(s) antígeno CD68
macrosialina
proteína 4 de membrana asociada al lisosoma
proteína LAMP4
proteína SCARD1
Scope note: Glicoproteína transmembrana de tipo 1 de paso único que se localiza en los LISOSOMAS, los ENDOSOMAS y las MEMBRANAS CELULARES de la superficie celular. Es miembro de la familia de glicoproteínas de membrana asociadas al lisosoma y de la familia de receptores depuradores. El dominio extracelular altamente glicosilado se une a LECTINAS o SELECTINAS específicas de tejidos y órganos.
Descriptor Portuguese: Molécula CD68
Descriptor French: Without translation
Entry term(s): Antigen, CD68
CD68 Antigen
LAMP4 Protein
Lysosomal Associated Membrane Protein 4
Lysosomal-Associated Membrane Protein 4
Macrosialin
SCARD1 Protein
Scavenger Receptor Class D, Member 1
Tree number(s): D09.400.430.890.550.125
D12.776.395.550.550.125
D12.776.543.550.527.125
D12.776.543.750.705.940.718.500
D12.776.543.750.710.450.750.718.500
D23.050.301.264.035.567
D23.050.301.264.900.023
D23.101.100.110.567
D23.101.100.900.023
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000097382
Scope note: A single-pass type 1 transmembrane glycoprotein that localizes to LYSOSOMES; ENDOSOMES; and cell surface CELL MEMBRANES. It is a member of the lysosomal associated membrane glycoprotein family and the scavenger receptor family. The highly glycosylated extracellular domain binds to tissue- and organ-specific LECTINS or SELECTINS.
Allowable Qualifiers: AD administration & dosage
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CH chemistry
CL classification
DE drug effects
DF deficiency
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PH physiology
RE radiation effects
TU therapeutic use
UL ultrastructure
Public MeSH Note: 2024; was indexed as ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC and ANTIGENS, CD 1991-2023
History Note: 2024 (1991)
DeCS ID: 60579
Unique ID: D000097382
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2024/01/01
Date of Entry: 2023/07/26
Revision Date: 2023/05/26
CD68 Molecule - Preferred
Concept UI M000763930
Scope note A single-pass type 1 transmembrane glycoprotein that localizes to LYSOSOMES; ENDOSOMES; and cell surface CELL MEMBRANES. It is a member of the lysosomal associated membrane glycoprotein family and the scavenger receptor family. The highly glycosylated extracellular domain binds to tissue- and organ-specific LECTINS or SELECTINS.
Preferred term CD68 Molecule
Entry term(s) Antigen, CD68
CD68 Antigen
LAMP4 Protein
Lysosomal Associated Membrane Protein 4
Lysosomal-Associated Membrane Protein 4
Macrosialin
SCARD1 Protein
Scavenger Receptor Class D, Member 1



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