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Descriptor English: Solute Carrier Family 12, Member 3
Descriptor Spanish: Miembro 3 de la Familia de Transportadores de Soluto 12
Descriptor miembro 3 de la familia de transportadores de solutos 12
Entry term(s) SLC12A3
miembro 3 de la familia 12 de transportadores de solutos
miembro 3 de la familia SLC 12
Scope note: Cotransportador de Na-Cl en los segmentos contorneados del TÚBULO DISTAL RENAL. Media la reabsorción activa de sodio y cloruro y es inhibido por los diuréticos tiazídicos ( = INHIBIDORES DE LOS SIMPORTADORES DEL CLORURO DE SODIO).
Descriptor Portuguese: Membro 3 da Família 12 de Carreador de Soluto
Descriptor French: Membre-3 de la famille-12 des transporteurs de solutés
Entry term(s): Cotransporter, Na-Cl
Cotransporter, Na-Cl Thiazide-Sensitive
Cotransporter, SLC12A3
Cotransporter, Thiazide-Sensitive Sodium-Chloride
NCCT Protein
Na Cl Cotransporter
Na Cl Symporter
Na Cl Thiazide Sensitive Cotransporter
Na-Cl Cotransporter
Na-Cl Symporter
Na-Cl Thiazide-Sensitive Cotransporter
Protein, NCCT
Protein, SLC12A3
SLC12A3 Cotransporter
SLC12A3 Protein
Sodium-Chloride Cotransporter, Thiazide-Sensitive
Symporter, Na-Cl
Thiazide Sensitive Sodium Chloride Cotransporter
Thiazide-Sensitive Cotransporter, Na-Cl
Thiazide-Sensitive Sodium-Chloride Cotransporter
Tree number(s): D12.776.157.530.450.625.374.500
D12.776.157.530.937.750.750
D12.776.543.585.937.875.750
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D064486
Scope note: Na-Cl cotransporter in the convoluted segments of the DISTAL KIDNEY TUBULE. It mediates active reabsorption of sodium and chloride and is inhibited by THIAZIDE DIURETICS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Entry Combination: antagonists & inhibitors:Sodium Chloride Symporter Inhibitors
Public MeSH Note: 2014; was indexed under CARRIER PROTEINS 1984-2001 and SODIUM CHLORIDE SYMPORTERS 2002-2013
History Note: 2014
Related: Gitelman Syndrome MeSH
DeCS ID: 55322
Unique ID: D064486
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2014/01/01
Date of Entry: 2013/07/08
Revision Date: 2015/11/24
Solute Carrier Family 12, Member 3 - Preferred
Concept UI M0581958
Scope note Na-Cl cotransporter in the convoluted segments of the DISTAL KIDNEY TUBULE. It mediates active reabsorption of sodium and chloride and is inhibited by THIAZIDE DIURETICS.
Preferred term Solute Carrier Family 12, Member 3
Entry term(s) Cotransporter, Na-Cl
Cotransporter, Na-Cl Thiazide-Sensitive
Cotransporter, SLC12A3
Cotransporter, Thiazide-Sensitive Sodium-Chloride
NCCT Protein
Na Cl Cotransporter
Na Cl Symporter
Na Cl Thiazide Sensitive Cotransporter
Na-Cl Cotransporter
Na-Cl Symporter
Na-Cl Thiazide-Sensitive Cotransporter
Protein, NCCT
Protein, SLC12A3
SLC12A3 Cotransporter
SLC12A3 Protein
Sodium-Chloride Cotransporter, Thiazide-Sensitive
Symporter, Na-Cl
Thiazide Sensitive Sodium Chloride Cotransporter
Thiazide-Sensitive Cotransporter, Na-Cl
Thiazide-Sensitive Sodium-Chloride Cotransporter



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